2017
DOI: 10.1038/s41598-017-07451-x
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: The intrinsic value of biodiversity extends beyond species diversity, genetic heritage, ecosystem variability and ecological services, such as climate regulation, water quality, nutrient cycling and the provision of reproductive habitats it is also an inexhaustible source of molecules and products beneficial to human well-being. To uncover the chemistry of Brazilian natural products, the Nuclei of Bioassays, Ecophysiology and Biosynthesis of Natural Products Database (NuBBEDB) was created as the first natural … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

3
164
0
1

Year Published

2018
2018
2021
2021

Publication Types

Select...
6
1

Relationship

0
7

Authors

Journals

citations
Cited by 153 publications
(168 citation statements)
references
References 58 publications
3
164
0
1
Order By: Relevance
“…Another interesting observation is that NuBEE DB and chemicals from marine organisms were closely correlated (Figure ) despite the fact that NuBBE DB has less than 1 % of compounds from marine sources and that the two collections overlap in just eight compounds (see Table S1 in the Supporting Information) . Curiously NATx was clustered together with the FDA dataset, but Figure and Figure show that NATx's p K a distributions of single acids and single bases, respectively, do not greatly differ from that found in natural products.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Another interesting observation is that NuBEE DB and chemicals from marine organisms were closely correlated (Figure ) despite the fact that NuBBE DB has less than 1 % of compounds from marine sources and that the two collections overlap in just eight compounds (see Table S1 in the Supporting Information) . Curiously NATx was clustered together with the FDA dataset, but Figure and Figure show that NATx's p K a distributions of single acids and single bases, respectively, do not greatly differ from that found in natural products.…”
Section: Resultsmentioning
confidence: 99%
“…NuBBE DB is a dataset of 2,218 compounds from Brazilian biodiversity, where 78 % of the compounds were isolated from plants, 5 % from microorganism, 0.2 % from marine organisms, 15 % are semisynthetic compounds, and 1.6 % are biotransformation products.…”
Section: Methodsmentioning
confidence: 99%
“…Nuclei of Bioassays, Ecophysiology and Biosynthesis of Natural Products Database (NuBBEDB) is a freely accessible database of Brazilian natural products, which provides validated multidisciplinary information, chemical descriptors, species sources, geographic locations, spectroscopic data (i.e., NMR), and pharmacological properties .…”
Section: Miscellaneous Tools Of Interestmentioning
confidence: 99%
“…The chemoinformatic analysis of several databases of NPs developed by academic institutions and private companies [21] has been carried out in different countries. Thus, the following databases were obtained: BIOFACQUIM [22], CIFPMA [23], NuBBE [24,25], NANPDB [26], TCM [27], HIT [28], and NPACT [29]. The application of chemoinformatic tools involves the generation, manipulation, and analysis of data set of chemical substances.…”
Section: Introductionmentioning
confidence: 99%