NQO1 polymorphism and susceptibility to ischemic stroke in a Chinese population
Min Wang,
Ying Shen,
Yuan Gao
et al.
Abstract:Background
Ischemic stroke (IS) is a major cause of death and disability worldwide. Genetic factors are important risk factors for the development of IS. The quinone oxidoreductase 1 gene (NQO1) has antioxidant, anti-inflammatory, and cytoprotective properties. Thus, in this study, we investigated the relationship between NQO1 gene polymorphism and the risk of IS.
Methods
Peripheral blood was collected from 143 patients with IS and 124 healthy controls in Yunnan, China, and NQO1 rs2917673, rs689455, and rs18… Show more
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