Abstract:At present heart failure treatment targets symptoms based on the left ventricle dysfunction severity; however, lack of systemic studies and available biological data to uncover heterogeneous underlying mechanisms on the scale of genomic, transcriptional and expressed protein level signifies the need to shift the analytical paradigm toward network centric and data mining approaches. This study, for the first time, aimed to investigate how bulk and single cell RNA-sequencing as well as the proteomics analysis of… Show more
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