Abstract:KEYWORDSTwo series of novel indole-2-carboxylic acid derivatives is reported. In the first series, Nsubstituted derivatives (3a-h) were synthesized via acylation of indole-2-carboxylic acid followed by aldol condensation reaction. Whereas, in the second series, indole-2-carboxamides (5a-g) were synthesized through conversion of acid to its acid chloride followed by coupling of substituted anilines. Structures of the newly synthesized compounds were confirmed by elemental analysis and spectral IR, 1 H NMR and m… Show more
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