“…Details on immunoblotting were summarized by us [9][10][11]. The following antibodies were used: ATR (2790S), CHK1 (2360), cleaved caspase-3 (9661), CRBN (71810), PARP1 (9542) and p-CHK1 (S345) from Cell Signaling, Leiden, Netherlands; ATM (ab32420), DNA-PKcs (ab32566) and p-ATM (T1981) (ab81292) from Abcam, Cambridge, UK; GSPT1 (sc-515 615), HSP90 (sc-13 119) and vinculin (sc-73 614) from Santa Cruz, Heidelberg, Germany; p-ATR (T1989) (GTX128145) from GeneTex, Irvine, MA, USA; ɣH2AX (S139) (MAB3802) from Millipore, Schwalbach, Germany.…”