Novel extraction, rapid assessment and bioavailability improvement of quercetin: A review

Manzoor, Muhammad Faisal; Hussain, Abid; Sameen, Aysha; Sahar, Amna; Khan, Sipper; Siddique, Rabia; Aadil, Rana Muhammad; Xu, Bin

doi:10.1016/j.ultsonch.2021.105686

Cited by 87 publications

(53 citation statements)

References 175 publications

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“…The increase in TPC and TFC in TS1, TS2, and TS3 as compared to the PSJ sample could be associated with the extended-release of bound polyphenols through high-intensity US treatments produced cell disruption, and these unbound polyphenols readily viable for the assay [38] . Moreover, during TS treatment increased phenolic compounds might be associated with the production of micro-cavities that enhance the mass transfer rate [39] , [40] , [41] . Comparable impacts of TS processing on TPC and TFC were recorded in blueberry wine [42] , blueberry juice [16] , and cloudy apple juice [43] .…”

Section: Resultsmentioning

confidence: 99%

Impact of high-intensity thermosonication treatment on spinach juice: Bioactive compounds, rheological, microbial, and enzymatic activities

Manzoor

Khan

et al. 2021

Ultrasonics Sonochemistry

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Highlights Temperature-controlled high-intensity thermosonication (TS) treatment is a useful sterilized method. TS processing improves the bioactive compounds and antioxidant activates, also caused color variations. TS treatments were reduced the particle size, and improve the suspension stability and rheological properties. High ultrasonic intensity TS treatment significantly reduced the microbial loads and enzymatic activities.

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Section: Resultsmentioning

confidence: 99%

Impact of high-intensity thermosonication treatment on spinach juice: Bioactive compounds, rheological, microbial, and enzymatic activities

Manzoor

Khan

et al. 2021

Ultrasonics Sonochemistry

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“…Quercetin is 3,5,7,3′,4′-pentahydroxyflavone that is commonly found in many vegetables and fruits [ 152 ]. The antioxidant potential of quercetin is approximately four times greater than that of vitamin E [ 153 ].…”

Section: Survey Of Antioxidants That Affected Bpa Toxicitymentioning

confidence: 99%

Can Antioxidants Reduce the Toxicity of Bisphenol?

2022

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BPA is still the subject of extensive research due to its widespread use, despite its significant toxicity resulting not only from its negative impact on the endocrine system but also from disrupting the organism’s oxidative homeostasis. At the molecular level, bisphenol A (BPA) causes an increased production of ROS and hence a change in the redox balance, mitochondrial dysfunction, and modulation of cell signaling pathways. Importantly, these changes accumulate in animals and humans, and BPA toxicity may be aggravated by poor diet, metabolic disorders, and coexisting diseases. Accordingly, approaches using antioxidants to counteract the negative effects of BPA are being considered. The preliminary results that are described in this paper are promising, however, it should be emphasized that further studies are required to determine the optimal dosage and treatment regimen to counteract BPA toxicity. It also seems necessary to have a more holistic approach showing, on the one hand, the influence of BPA on the overall human metabolism and, on the other hand, the influence of antioxidants in doses that are acceptable with the diet on BPA toxicity. This is due in part to the fact that in many cases, the positive effect of antioxidants in in vitro studies is not confirmed by clinical studies. For this reason, further research into the molecular mechanisms of BPA activity is also recommended.

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“…One of the compounds classed as one of the flavonoids, which consist of three condensed rings and five hydroxyl groups, is quercetin (3, 5, 7, 3′, 4′-pentahydroxyflavone), a compound present in fruits, vegetables, wine, tea, etc. [ 34 ]. Metal ions, including Cu (II), can significantly change the chemical properties of quercetin, influencing its antioxidant and biological activity.…”

Section: Introductionmentioning

confidence: 99%

Assessment of the Impact of the Application of a Quercetin—Copper Complex on the Course of Physiological and Biochemical Processes in Wheat Plants (Triticum aestivum L.) Growing under Saline Conditions

Jańczak-Pieniążek

Migut

Piechowiak

et al. 2022

Cells

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Salt stress is one of the main stressors limiting plant growth and yield. As a result of salt stress, unfavorable changes in the photosynthesis process take place, leading to a decrease in plant productivity. Therefore, it is necessary to use biologically active substances that reduce the effects of this stress. An example of such a substance is quercetin, classified as a flavonoid, which plays an important role in alleviating the effects of salt stress, mainly by the inactivation of reactive oxygen species (ROS) and by improvement of the photosynthesis process. A study was made of the effect of the quercetin–copper complex (Q-Cu (II)), which has a stronger antioxidant effect than pure quercetin. By means of a pot experiment, the influence of solutions of the Q-Cu (II) complex (100 mg∙L−1 [Q1], 500 mg∙L−1 [Q2] and 1000 mg∙L−1 [Q3]) on the physiological and biochemical processes occurring in wheat plants subjected to salt stress was investigated. The plants were given two sprays of Q-Cu (II) solution, and their physiological parameters were examined both 1 and 7 days after each application of this solution. The level of ROS and the activity of antioxidant enzymes (catalase [CAT], superoxide dismutase [SOD] and guaiacol peroxidase [GPOX]) were also determined. It has been shown that spraying with Q2 and Q3 solutions improves the chlorophyll content, the values of chlorophyll fluorescence parameters (the photochemical efficiency of PS II [Fv/Fm], the maximum quantum yield of primary photochemistry [Fv/F0], and the performance index of PS II [PI]), and gas exchange (net photosynthetic rate [Pn], stomatal conductance [gs], transpiration rate [E] and intercellular CO2 concentration [Ci]). As a result of the application of Q2 and Q3 solutions, the level of ROS and the activity of the antioxidant enzymes tested decreased, which means that these concentrations are most effective in counteracting the effects of salt stress.

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Novel extraction, rapid assessment and bioavailability improvement of quercetin: A review

Abstract: Graphical abstract

Cited by 87 publications

References 175 publications

Impact of high-intensity thermosonication treatment on spinach juice: Bioactive compounds, rheological, microbial, and enzymatic activities

Impact of high-intensity thermosonication treatment on spinach juice: Bioactive compounds, rheological, microbial, and enzymatic activities

Can Antioxidants Reduce the Toxicity of Bisphenol?

Assessment of the Impact of the Application of a Quercetin—Copper Complex on the Course of Physiological and Biochemical Processes in Wheat Plants (Triticum aestivum L.) Growing under Saline Conditions

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