Novel bis(1-acyl-2-pyrazolines) of potential anti-inflammatory and molluscicidal properties

Synthesis, Characterisation and Biological Screening of s-Triazine Based Chalcones and its Derivatization into Phenyl Pyrazolines, Isoxazoles

“…Various chalcone derivatives are remarkable materials for their second harmonic generation [6]. They are naturally occurring plant metabolites possess a broad spectrum of biological activities such as cancer cell lines [7][8], antimitotic [9], antiinflammatory [10], hepatoprotective [11], molluscicidal properties [12], heme oxygenase-1 [13], antimicrobial [14] etc... . So, this broad spectrum of applications encouraged us to search for another addition to the existed molecule.…”

Synthesis, characterization and antimicrobial evaluation of 1-((5,3-diaryl)-4,5-dihydro-1H-pyrazol-1-yl)propan-1-one

“…Over the years, the chemistry of 1H-pyrazoles has received considerable attention [1,2]. It is worthy of note that substances containing a 1H-pyrazole moiety have been described as having potential therapeutic utility, such as antiinflammatory [3][4][5], antidepressant [6,7], antipyretic [8], antibacterial [9][10][11][12][13][14], antifungal [12,15] and antitumoral [16]. Of particular interest is the use of 1H-pyrazoles as synthetic intermediates for preparing cyclopropane [17][18][19] and pyrazole derivatives [1,[20][21][22][23][24][25][26].…”

Synthesis and evaluation of DPPH and anti-inflammatory activities of 2,6-bisbenzylidenecyclohexanone and pyrazoline derivatives

“…This class of compounds has been known to exhibit potent antiinflammatory activities (Bansal et al, 2001;Barsoum et al, 2006;Rani et al, 2004). In this study, a series of active NO inhibitors of 2,6-bisbenzylidenecyclohexanone derivatives merging with the active pyrazoline moiety were synthesized and evaluated for their anti-inflammatory properties.…”