Abstract:Background: Ras and Rab interactor 2 (RIN2) gene, encoding RAS and Rab interacting protein 2, can interact with GTP-bound Rab5 and participate in early endocytosis. Deletion of RIN2 may impair Rab5-related endosome signaling, leading to abnormal phenotypes. However, no research has been reported on the functions of RIN2 related to animal production.Results: A 61-bp insertion/deletion (indel) in the RIN2 intron region in this study. The genotype analysis of mutation sites was performed on 550 individuals from 7… Show more
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