Nothing is impossible: radiation induced angiosarcoma of breast in a male patient

Tsapralis, Nikolaos; Vlachogiorgos, Apostolos; Pham, Hien; Mowatt, David

doi:10.1093/jscr/rjz158

Cited by 6 publications

(2 citation statements)

References 7 publications

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“…Moreover, the diagnosis of RIAS was also described in a patient who had partial breast radiotherapy [ 17 ]. Recently, RIAS was also described in a male patient [ 18 ]. In this study, the MYC was not evaluated [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

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A Case Report of Post-Radiotherapy c-MYC-Positive Angiosarcoma of the Breast

et al. 2022

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Angiosarcoma of the breast is an unusual malignancy and carries a poor prognosis, with a 5-year overall survival rate ranging from 27 to 48%. Radiotherapy-induced angiosarcoma (RIAS) of the breast is very uncommon, with an estimated incidence of 1 in 1,000 cases of breasts treated with radiotherapy for breast cancer. The increase in radiotherapy usage may lead to an increased incidence of RIAS. A case presentation of a 67-year-old patient with tubular adenocarcinoma of the left breast who developed c-MYC-positive RIAS of the breast is presented. The patient was successfully treated with surgery. We presented a classic case of c-MYC RIAS. c-MYC was reported to be positive in RIAS and other types of angiosarcomas. Clinical examination and early detection of RIAS breast angiosarcoma is vital to improving outcomes in these patients.

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Section: Discussionmentioning

confidence: 99%

“…Recently, RIAS was also described in a male patient [ 18 ]. In this study, the MYC was not evaluated [ 18 ].…”

Section: Discussionmentioning

confidence: 99%