Notch Protein as Leading Cause of World Cancer Epidemic

Abstract

Compared to patients who chose evidence-based cancer treatments, those who used unconventional methods tended to have high social and economic status (be from northwestern U.S. states), have advanced cancers and be in otherwise good health. The problem is, that people who decide to tackle their cancer using only unconventional methods are likely die sooner than patients who opt for conventional treatments, according to a new study. Mouse model shows that Notch activation can drive metastatic prostate, colon and other types of cancer. Notch protein complex signaling pathway is in our view one of the most important cause of the World Cancer Epidemic.