Not 15 But 50% of smokers develop COPD?—Report from the Obstructive Lung Disease in Northern Sweden Studies

Lundbäck, Bo; Lindberg, Anne; Lindström, Maj; Rönmark, Eva; Jonsson, Ann-Christin; Jonsson, E. Niclas; Larsson, Lars‐Gunnar; Andersson, Staffan; Sandström, Thomas; Larsson, Kjell

doi:10.1053/rmed.2003.1446

Cited by 504 publications

(417 citation statements)

References 27 publications

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“…[1][2][3][4][5][6][7][8][9] According to the Global Burden of Disease Study, 1,2 COPD will be the fifth-leading cause of disability and the third-leading cause of death in the world in the first half of the 21st century. For developing countries, COPD is expected to be the fourth cause of disability for men and the third cause of disability for women by 2020.…”

mentioning

confidence: 99%

Diagnostic Labeling of COPD in Five Latin American Cities

Tálamo

Halbert

et al. 2007

Chest

120

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mentioning

confidence: 99%

Diagnostic Labeling of COPD in Five Latin American Cities

Tálamo

Halbert

et al. 2007

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120

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“…The primary cause of COPD is tobacco smoking and the risk of developing COPD among smokers is more than 40% [6]. Despite a massive effort with several campaigns to promote smoking cessation/preventing the initiation of smoking as well as banning smoking in public places in Denmark since 2007, approximately 17% of the Danish population above 15 years were daily smokers in 2016 with no difference between genders.…”

Section: Introductionmentioning

confidence: 99%

“…breathlessness) and disabilities as a life condition rather than an illness [11]. Moreover, patients with COPD are often under-or misdiagnosed [6,12–14]. Therefore, increased awareness in the general population about COPD is an important factor in the diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Lack of awareness towards smoking-related health risks, symptoms related to COPD, and attitudinal factors concerning smoking: an Internet-based survey conducted in a random sample of the Danish general population

Sikjær

Hilberg

Fløe

et al. 2018

European Clinical Respiratory Journal

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Background: Although chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality globally, several studies have shown little awareness of COPD in the general population. The awareness of COPD in the Scandinavian countries is, however, sparsely investigated. Objective: The aim of this study was to explore the awareness in the general Danish population of smoking-related health risks and symptoms related to COPD and attitudinal factors concerning smoking. Design: Adults aged 18 years or older were randomly selected to reflect the background population. An Internet-based questionnaire was conducted in January–February 2015. Results: A total of 1002 answered the questionnaire (515 males; 487 females). In total, 17.7% were current smokers (men: 15.5%–women: 19.9%). More smokers and ex-smokers knew the symptoms of COPD compared to never-smokers (p < 0.001). Ex-smokers had undergone more pulmonary function tests than smokers and never-smokers (p < 0.001) and significantly more men than women who had undergone pulmonary function test.Ex-smokers were more likely to rate cancer as the most feared disease (p = 0.026) than the smokers. Of the smokers, 28% did not regard COPD as a deadly disease and significantly more smokers than ex-/never-smokers believed that smoking cessation should not be mandatory before treatment of COPD and asthma (p < 0.001). Conclusion: Overall, smokers, ex-, and never-smokers had little knowledge of COPD regarding aetiology, symptoms, and severity thus emphasizing the necessity of early detection of COPD and more focus on spirometry in general practice, especially amongst smokers.There is a great discrepancy between the attitude of smokers and ex-/never-smokers towards mandatory smoking cessation before receiving treatment of smoking-related diseases. Funding: GlaxoSmithKline Pharma A/S Brøndby, financially supported the collecting of data by Voxmeter A/S. The authors had full access to the raw data and did not receive any financially support.

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“…Chronic obstructive pulmonary disease (COPD) is a common disease strongly associated with increasing age and environmental exposure, most commonly own tobacco smoke exposure [1] but globally also indoor exposure to biofuel combustion exhaust [2]. The prevalence of COPD is generally reported in the range of 8–10% among adults.…”

Section: Introductionmentioning

confidence: 99%

From COPD epidemiology to studies of pathophysiological disease mechanisms: challenges with regard to study design and recruitment process

Lindberg

Linder

Bäckman

et al. 2017

European Clinical Respiratory Journal

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Background: Chronic obstructive pulmonary disease (COPD) is a largely underdiagnosed disease including several phenotypes. In this report, the design of a study intending to evaluate the pathophysiological mechanism in COPD in relation to the specific phenotypes non-rapid and rapid decline in lung function is described together with the recruitment process of the study population derived from a population based study. Method: The OLIN COPD study includes a population-based COPD cohort and referents without COPD identified in 2002–04 (n = 1986), and thereafter followed annually since 2005. Lung function decline was estimated from baseline in 2002–2004 to 2010 (first recruitment phase) or to 2012/2013 (second recruitment phase). Individuals who met the predefined criteria for the following four groups were identified; group A) COPD grade 2–3 with rapid decline in FEV1 and group B) COPD grade 2–3 without rapid decline in FEV1 (≥60 and ≤30 ml/year, respectively), group C) ever-smokers, and group D) non-smokers with normal lung function. Groups A–C included ever-smokers with >10 pack years. The intention was to recruit 15 subjects in each of the groups A-D. Results: From the database groups A–D were identified; group A n = 37, group B n = 29, group C n = 41, and group D n = 55. Fifteen subjects were recruited from groups C and D, while this goal was not reached in the groups A (n = 12) and B (n = 10). The most common reasons for excluding individuals identified as A or B were comorbidities contraindicating bronchoscopy, or inflammatory diseases/immune suppressive medication expected to affect the outcome. Conclusion: The study is expected to generate important results regarding pathophysiological mechanisms associated with rate of decline in lung function among subjects with COPD and the in-detail described recruitment process, including reasons for non-participation, is a strength when interpreting the results in forthcoming studies.

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Not 15 But 50% of smokers develop COPD?—Report from the Obstructive Lung Disease in Northern Sweden Studies

Cited by 504 publications

References 27 publications

Diagnostic Labeling of COPD in Five Latin American Cities

Diagnostic Labeling of COPD in Five Latin American Cities

Lack of awareness towards smoking-related health risks, symptoms related to COPD, and attitudinal factors concerning smoking: an Internet-based survey conducted in a random sample of the Danish general population

From COPD epidemiology to studies of pathophysiological disease mechanisms: challenges with regard to study design and recruitment process

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