Normolipemic Plane Xanthomas

Fleischmajer, Raúl

doi:10.1001/archderm.1964.01590270005001

Cited by 19 publications

(7 citation statements)

References 5 publications

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“…7 Lately, however, methods for more detailed study of lipids and lipopro¬ teins have become available. Elevat¬ ed /3-lipoprotein fractions have been demonstrated in patients with nor¬ mal total serum lipids.41" This report was prompted by the finding, in a patient with diffuse plane xanthoma and standard lipid values within normal limits, not only of a distinct lipoprotein abnormality but also of a kind that we have not found de¬ scribed previously.…”

Section: Commentmentioning

confidence: 99%

Serum Lipoprotein Deficiency in Diffuse "Normolipemic" Plane Xanthoma

Lindeskog¹

1972

Arch Dermatol

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Section: Commentmentioning

confidence: 99%

Serum Lipoprotein Deficiency in Diffuse "Normolipemic" Plane Xanthoma

Lindeskog¹

1972

Arch Dermatol

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“…[15] Some authors believe that the lesion is due to secondary xanthomatization induced by previously infiltrating cells. [16] There might not be a single pathogenic mechanism to explain all cases of NPX.…”

Section: Discussionmentioning

confidence: 99%

Cutaneous Normolipemic Plane Xanthoma with Supraglottic Involvement in a Patient with Hand-Schüller-Christian Disease

Chen

Chung

et al. 2009

American Journal of Clinical Dermatology

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Normolipemic plane xanthoma (NPX) is a histiocytic disorder characterized by yellow-orange plaques in the periorbital areas, neck, upper trunk, and flexural folds. Association with systemic disease or paraproteinemia has been reported previously, but rarely with Langerhans cell histiocytosis (LCH). We report a case of Hand-Schüller-Christian disease (a type of LCH) in a patient who developed NPX with supraglottic involvement. NPX developed after several courses of chemotherapy and the supraglottic xanthoma occurred about 2 years later. The coexistence of LCH and non-LCH histiocytic lesions in this patient could be a result of chemotherapy-induced changes or may be just coincidental.

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“…Not all cases of xanthoma following inflammatory dermatoses are associated with photosensitivity. Fleischmayer, Hyman & Weidman (1964) reported xanthoma occurring in one patient after an unspecified rash and in another patient following measles. Both patients were normolipaemic.…”

Section: Discussionmentioning

confidence: 99%

Plane xanthoma developing in photosensitive eczema. A REPORT OF THREE CASES WITH A DISCUSSION OF A POSSIBLE MECHANISM FOR LIPID ACCUMULATION IN PLANE XANTHOMAS

James

Warin

1978

Clin Exp Dermatol

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Summary Three cases of plane xanthoma arising in chronic eczema are described. Two patients had long standing photosensitive eczema and the other actinic reticuloid. It is suggested that foam cells develop from dermal macrophages in chronically inflamed skin. Lipid accumulation may be due to a failure of a specific receptor‐mediated control of cholesterol uptake into macrophages and be independent of circulating plasma lipid or lipoprotein levels.

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Normolipemic Plane Xanthomas

Cited by 19 publications

References 5 publications

Serum Lipoprotein Deficiency in Diffuse "Normolipemic" Plane Xanthoma

Serum Lipoprotein Deficiency in Diffuse "Normolipemic" Plane Xanthoma

Cutaneous Normolipemic Plane Xanthoma with Supraglottic Involvement in a Patient with Hand-Schüller-Christian Disease

Plane xanthoma developing in photosensitive eczema. A REPORT OF THREE CASES WITH A DISCUSSION OF A POSSIBLE MECHANISM FOR LIPID ACCUMULATION IN PLANE XANTHOMAS

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