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Cited by 85 publications
(98 citation statements)
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References 36 publications
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“…In the older participant group, consistent with several previous reports, we also found higher blood pressure to be associated with poorer performance on cognitive measures (e.g., Elias et al, 1993;Kilander et al, 1998;Knopman et al, 2001;Swan et al, 1998b;Tzourio et al, 1999) and smaller brain volumes (e.g., Akiyama et al, 1997;Swan et al, 1998a). Systolic blood pressure but not stroke risk showed a significant association with cognition.…”
Section: Discussionsupporting
confidence: 91%
See 1 more Smart Citation
“…In the older participant group, consistent with several previous reports, we also found higher blood pressure to be associated with poorer performance on cognitive measures (e.g., Elias et al, 1993;Kilander et al, 1998;Knopman et al, 2001;Swan et al, 1998b;Tzourio et al, 1999) and smaller brain volumes (e.g., Akiyama et al, 1997;Swan et al, 1998a). Systolic blood pressure but not stroke risk showed a significant association with cognition.…”
Section: Discussionsupporting
confidence: 91%
“…In contrast, other have shown the coupling of age-related atrophy with decreases in perfusion (Kaszniak et al, 1979;Kety et al, 1956;Meyer et al, 1994), suggesting that atrophy results in reduced cerebral metabolism. Positron emission tomography (PET) and single photon emission computed tomography (SPECT) studies have shown age-related reductions in both global CBF (Akiyama et al, 1997;Hagstadius and Risberg, 1989;Krausz et al, 1998;Matsuda et al, 2003) as well as regional CBF in the medial temporal lobe (MTL; Krausz et al, 1998), parahippocampus (Martin et al, 1991;Matsuda et al, 2003) and hippocampus (Larsson et al, 2001;Tanaka et al, 2000).…”
Section: Introductionmentioning
confidence: 99%
“…Recent brain neuroimaging studies reported structural abnormalities in non-alcoholic chronic smokers. Specifically, MRI indicated smaller neocortical GM volumes and lower densities in the prefrontal cortex, smaller left anterior cingulate volume, and lower GM densities in the right cerebellum of chronic smokers compared to non-smokers (Brody et al, 2004), and computed tomography showed increased generalized brain atrophy with advancing age in chronic smokers (Akiyama et al, 1997;Hayee et al, 2003;Kubota et al, 1987). Volume reductions in these regions are also commonly reported in alcoholism (see Sullivan, 2000, for review).…”
Section: Discussionmentioning
confidence: 98%
“…In males, right gray matter was somewhat larger than left gray matter (F[1,38]= 6.92, p=0.0123), but in females, left gray matter was larger (F[1,100]=5.27, p < 0.0237). In males, left white matter was somewhat larger than right white matter (F [1,38]=7.24, p < 0.0105) but in females, right white matter was larger (F[1,100] =4.84, p < 0.0301). In Table 2, all results for hemisphere and the hemisphere × gender interaction are reported; the simple effects of gender are reported in Analysis 3.…”
Section: Analysis 1: Lateralitymentioning
confidence: 99%
“…Moreover, many of these studies did not provide quantitative estimates of the rate of atrophy, instead presenting correlations or analyses of variance that compared different age groups; others have used relatively imprecise rating scales, particularly when measuring whitematter hyperintensities. Given previous findings of an increase in the rate of decline among the elderly [1], we decided to focus on an elderly population. We investigated the rate of volume change in gray and white matter tissue, cerebrospinal fluid, and lesions, as well as the caudate, putamen, and hippocampus.…”
Section: Introductionmentioning
confidence: 99%