Normal anatomy of the developing fetal brain. Ex vivo anatomical–magnetic resonance imaging correlation

Prenatal cerebral magnetic resonance imaging

“…It is in line with a previous study, in which the appearance of the fetal brain, at different stages of gestation, was analyzed in postmortem normal fetal brains, employing MRI and anatomically dissecting them [3].…”

“…The normal cortical development can be easily recognized in fetal brain MRIs. Sulcal and gyral maturation follows a precise and predetermined sequence that has been extensively studied either in vitro, by MRI or employing both methods [1][2][3]7,12,[14][15][16]18,20,23]. This cortical morphological analysis allows calculating the fetal age with an error that fluctuates between 1 and 2 weeks, as other embryological methods.…”

White Matter Characteristics and Cognition in Prenatally Opiate- and Polysubstance-Exposed Children: A Diffusion Tensor Imaging Study

“…With the exception of a cluster in the Fmin, all effects were located in relatively central, posterior, and inferior parts of the brain. This is where myelination occurs relatively early in CNS development, 18,36 and differences in these areas can be interpreted as corresponding to agents of early influence, though a number of potential confounds must also be considered. There were, to a somewhat greater extent, more group differences in DR than in DA across clusters.…”

Nomograms of the Fetal Sylvian Fissure and Insular Lobe throughout Gestation: A Multicentric, Ultrasonographic Cross-Sectional Study

“…This is crucial for identifying an impaired neuronal migration in conditions that may affect brain development, such as intrauterine growth restriction or congenital heart disease, or lissencephaly [23][24][25][26][27][28][29][30][31][32][33]. Prenatal diagnosis of an affected fetus may also be of value as this allows appropriate counseling, optimization of obstetric management [26][27][28][29][30][31][32][33], and planning of further future examinations [34].…”