Nonsteroidal Anti-inflammatory Drugs and Cataract Surgery

Comparative Effects of Topical Diclofenac and Betamethasone on Inflammation After Vitrectomy and Cataract Surgery in Various Vitreoretinal Diseases

“…Although both drug classes have anti-inflammatory effects, topical NSAIDs are more effective than topical steroids in reestablishing the blood–aqueous barrier, as measured by anterior ocular fluorophotometry. 16 Moreover, these 2 classes are equally effective in suppressing postoperative inflammation and IOP elevation.…”

Comparative Effects of Topical Diclofenac and Betamethasone on Inflammation After Vitrectomy and Cataract Surgery in Various Vitreoretinal Diseases

“…Although both drug classes have anti-inflammatory effects, topical NSAIDs are more effective than topical steroids in reestablishing the blood–aqueous barrier, as measured by anterior ocular fluorophotometry. 16 Moreover, these 2 classes are equally effective in suppressing postoperative inflammation and IOP elevation.…”

Topical nepafenac 0.1% alone versus prednisolone acetate 1% as postoperative anti-inflammatory agents in small gauge vitrectomy

“…Topical NSAIDs appear more effective than topical steroids in re-establishing the blood-aqueous barrier, as quantitatively measured with anterior ocular fluorophotometry. [19] In a study by Miyake et al .,[20] nepafenac was found to be more effective than fluorometholone in preventing angiographic CME and blood aqueous barrier disruption, and the results indicated that nepafenac led to more rapid visual recovery. Lane et al .,[4] also, in a prospective randomized double-blinded study, showed an unequivocal reduction in post cataract surgery pain and inflammation in patients receiving topical nepafenac.…”

Role of Topical Nepafenac in Prevention and Treatment of Macular Edema After Vitreoretinal Surgery

“…[1][2][3]12 Interestingly, topical NSAIDs appear more effective than topical steroids in reestablishing the blood-aqueous barrier as quantitatively measured with anterior ocular fluorophotometry. 13 Nepafenac is a new NSAID that has been approved by the U.S. Food and Drugs Administration for the treatment of pain and inflammation after cataract surgery. 4 Being a prodrug with greater ocular penetration, it hydrolyzes within ocular tissues, resulting in greater intraocular concentration of its active metabolite amfenac.…”

Comparative Effects of Topical Diclofenac and Betamethasone on Inflammation After Vitrectomy and Cataract Surgery in Various Vitreoretinal Diseases

“…Although both drug classes have anti-inflammatory effects, topical NSAIDs are more effective than topical steroids in reestablishing the blood–aqueous barrier, as measured by anterior ocular fluorophotometry. 16 Moreover, these 2 classes are equally effective in suppressing postoperative inflammation and IOP elevation.…”

Topical nepafenac 0.1% alone versus prednisolone acetate 1% as postoperative anti-inflammatory agents in small gauge vitrectomy

“…Topical NSAIDs appear more effective than topical steroids in re-establishing the blood-aqueous barrier, as quantitatively measured with anterior ocular fluorophotometry. [19] In a study by Miyake et al .,[20] nepafenac was found to be more effective than fluorometholone in preventing angiographic CME and blood aqueous barrier disruption, and the results indicated that nepafenac led to more rapid visual recovery. Lane et al .,[4] also, in a prospective randomized double-blinded study, showed an unequivocal reduction in post cataract surgery pain and inflammation in patients receiving topical nepafenac.…”

Role of Topical Nepafenac in Prevention and Treatment of Macular Edema After Vitreoretinal Surgery

“…[1][2][3]12 Interestingly, topical NSAIDs appear more effective than topical steroids in reestablishing the blood-aqueous barrier as quantitatively measured with anterior ocular fluorophotometry. 13 Nepafenac is a new NSAID that has been approved by the U.S. Food and Drugs Administration for the treatment of pain and inflammation after cataract surgery. 4 Being a prodrug with greater ocular penetration, it hydrolyzes within ocular tissues, resulting in greater intraocular concentration of its active metabolite amfenac.…”

Comparative Effects of Topical Diclofenac and Betamethasone on Inflammation After Vitrectomy and Cataract Surgery in Various Vitreoretinal Diseases

“…Although both drug classes have anti-inflammatory effects, topical NSAIDs are more effective than topical steroids in reestablishing the blood–aqueous barrier, as measured by anterior ocular fluorophotometry. 16 Moreover, these 2 classes are equally effective in suppressing postoperative inflammation and IOP elevation.…”

Topical nepafenac 0.1% alone versus prednisolone acetate 1% as postoperative anti-inflammatory agents in small gauge vitrectomy

“…Topical NSAIDs appear more effective than topical steroids in re-establishing the blood-aqueous barrier, as quantitatively measured with anterior ocular fluorophotometry. [19] In a study by Miyake et al .,[20] nepafenac was found to be more effective than fluorometholone in preventing angiographic CME and blood aqueous barrier disruption, and the results indicated that nepafenac led to more rapid visual recovery. Lane et al .,[4] also, in a prospective randomized double-blinded study, showed an unequivocal reduction in post cataract surgery pain and inflammation in patients receiving topical nepafenac.…”

Role of Topical Nepafenac in Prevention and Treatment of Macular Edema After Vitreoretinal Surgery

“…[1][2][3]12 Interestingly, topical NSAIDs appear more effective than topical steroids in reestablishing the blood-aqueous barrier as quantitatively measured with anterior ocular fluorophotometry. 13 Nepafenac is a new NSAID that has been approved by the U.S. Food and Drugs Administration for the treatment of pain and inflammation after cataract surgery. 4 Being a prodrug with greater ocular penetration, it hydrolyzes within ocular tissues, resulting in greater intraocular concentration of its active metabolite amfenac.…”