Nonpharmacologic Versus Pharmacologic Treatment of Adult Patients With Major Depressive Disorder: A Clinical Practice Guideline From the American College of Physicians

Abstract

ACP recommends that clinicians select between either cognitive behavioral therapy or second-generation antidepressants to treat patients with major depressive disorder after discussing treatment effects, adverse effect profiles, cost, accessibility, and preferences with the patient (Grade: strong recommendation, moderate-quality evidence).

A Meta-analysis of Different Acupuncture Modalities Combined With Antidepressants to Reduce Major Depressive Disorder

“…Similar to our findings, Smith et al reported that acupuncture (MA and LA) could moderately reduce the severity of depression 14 . Chen et al 28 found that acupuncture had potential as a monotherapy and as an adjunct to antidepressants in treating patients with MDD, which was consistent with current American College of Physicians clinical practice guidelines 29 . It has been shown that SA may stimulate the body's natural physiological responses such as analgesia, anti-inflammatory responses, 30 and physiological changes in blood circulation and neural pathways 31 .…”

A Meta-analysis of Different Acupuncture Modalities Combined With Antidepressants to Reduce Major Depressive Disorder

“…Similar to our findings, Smith et al reported that acupuncture (MA and LA) could moderately reduce the severity of depression 14 . Chen et al 28 found that acupuncture had potential as a monotherapy and as an adjunct to antidepressants in treating patients with MDD, which was consistent with current American College of Physicians clinical practice guidelines 29 . It has been shown that SA may stimulate the body's natural physiological responses such as analgesia, anti-inflammatory responses, 30 and physiological changes in blood circulation and neural pathways 31 .…”

Efficacy and safety of acupuncture for depression: A systematic review and meta‐analysis

“…Our findings provided updated evidence in line with the current American College of Physicians clinical practice guideline suggesting acupuncture as a potential monotherapy and combination therapy with antidepressants in treating patients with MDD (Qaseem et al, 2016 ). We hope that our study can aid in filling the existing gap between research findings and clinical practice.…”

Complementary therapies for clinical depression: an overview of systematic reviews

“…Particularly for bridging the gap between diagnosis and getting access to psychotherapy and meanwhile reducing/not-worsening depression severity, St. John’s wort may be considered as a possibly better tolerated alternative to standard antidepressant drugs 167. As St. John’s wort is accessible without prescription and currently not regulated by the US Food and Drug Administration, we agree with the ACP guidelines31 that it remains difficult for patients to obtain quality-controlled remedies. Moreover, St. John’s wort is associated with numerous herb-to-drug interactions 168.…”

A Meta-analysis of Different Acupuncture Modalities Combined With Antidepressants to Reduce Major Depressive Disorder

“…Similar to our findings, Smith et al reported that acupuncture (MA and LA) could moderately reduce the severity of depression 14 . Chen et al 28 found that acupuncture had potential as a monotherapy and as an adjunct to antidepressants in treating patients with MDD, which was consistent with current American College of Physicians clinical practice guidelines 29 . It has been shown that SA may stimulate the body's natural physiological responses such as analgesia, anti-inflammatory responses, 30 and physiological changes in blood circulation and neural pathways 31 .…”

Efficacy and safety of acupuncture for depression: A systematic review and meta‐analysis

“…Our findings provided updated evidence in line with the current American College of Physicians clinical practice guideline suggesting acupuncture as a potential monotherapy and combination therapy with antidepressants in treating patients with MDD (Qaseem et al, 2016 ). We hope that our study can aid in filling the existing gap between research findings and clinical practice.…”

Complementary therapies for clinical depression: an overview of systematic reviews

“…Particularly for bridging the gap between diagnosis and getting access to psychotherapy and meanwhile reducing/not-worsening depression severity, St. John’s wort may be considered as a possibly better tolerated alternative to standard antidepressant drugs 167. As St. John’s wort is accessible without prescription and currently not regulated by the US Food and Drug Administration, we agree with the ACP guidelines31 that it remains difficult for patients to obtain quality-controlled remedies. Moreover, St. John’s wort is associated with numerous herb-to-drug interactions 168.…”

A Meta-analysis of Different Acupuncture Modalities Combined With Antidepressants to Reduce Major Depressive Disorder

“…Similar to our findings, Smith et al reported that acupuncture (MA and LA) could moderately reduce the severity of depression 14 . Chen et al 28 found that acupuncture had potential as a monotherapy and as an adjunct to antidepressants in treating patients with MDD, which was consistent with current American College of Physicians clinical practice guidelines 29 . It has been shown that SA may stimulate the body's natural physiological responses such as analgesia, anti-inflammatory responses, 30 and physiological changes in blood circulation and neural pathways 31 .…”

Efficacy and safety of acupuncture for depression: A systematic review and meta‐analysis

“…Our findings provided updated evidence in line with the current American College of Physicians clinical practice guideline suggesting acupuncture as a potential monotherapy and combination therapy with antidepressants in treating patients with MDD (Qaseem et al, 2016 ). We hope that our study can aid in filling the existing gap between research findings and clinical practice.…”

Complementary therapies for clinical depression: an overview of systematic reviews

“…Particularly for bridging the gap between diagnosis and getting access to psychotherapy and meanwhile reducing/not-worsening depression severity, St. John’s wort may be considered as a possibly better tolerated alternative to standard antidepressant drugs 167. As St. John’s wort is accessible without prescription and currently not regulated by the US Food and Drug Administration, we agree with the ACP guidelines31 that it remains difficult for patients to obtain quality-controlled remedies. Moreover, St. John’s wort is associated with numerous herb-to-drug interactions 168.…”