Nonhealing Leg Ulceration—Quiz Case

Skin Infections

“…1016 They usually have a slowly progressive course with no tendency to self-heal. 1030 Usually, there is a chronic granulomatous reaction throughout the dermis, which may also involve the subcutaneous tissue, associated with a variable admixture of lymphocytes, neutrophils, plasma cells, and occasional eosinophils. 1016,1020,[1023][1024][1025][1026][1027][1028] Lesions resembling herpes, eczema, subcutaneous mycoses, and pyoderma gangrenosum have also been described.…”

“…1017 The epidermis can exhibit hyperkeratosis, focal parakeratosis, and pseudoepitheliomatous hyperplasia. 1016,1020,1021,1023,[1030][1031][1032] Prototheca species are spherical, unicellular organisms ranging from 3 to 30 µm in diameter. They manifest as thick-walled, spherical bodies with no budding.…”

Skin Infections

“…1016 They usually have a slowly progressive course with no tendency to self-heal. 1030 Usually, there is a chronic granulomatous reaction throughout the dermis, which may also involve the subcutaneous tissue, associated with a variable admixture of lymphocytes, neutrophils, plasma cells, and occasional eosinophils. 1016,1020,[1023][1024][1025][1026][1027][1028] Lesions resembling herpes, eczema, subcutaneous mycoses, and pyoderma gangrenosum have also been described.…”

“…1017 The epidermis can exhibit hyperkeratosis, focal parakeratosis, and pseudoepitheliomatous hyperplasia. 1016,1020,1021,1023,[1030][1031][1032] Prototheca species are spherical, unicellular organisms ranging from 3 to 30 µm in diameter. They manifest as thick-walled, spherical bodies with no budding.…”

Skin Infections

“…1016 They usually have a slowly progressive course with no tendency to self-heal. 1030 Usually, there is a chronic granulomatous reaction throughout the dermis, which may also involve the subcutaneous tissue, associated with a variable admixture of lymphocytes, neutrophils, plasma cells, and occasional eosinophils. 1016,1020,[1023][1024][1025][1026][1027][1028] Lesions resembling herpes, eczema, subcutaneous mycoses, and pyoderma gangrenosum have also been described.…”

“…1017 The epidermis can exhibit hyperkeratosis, focal parakeratosis, and pseudoepitheliomatous hyperplasia. 1016,1020,1021,1023,[1030][1031][1032] Prototheca species are spherical, unicellular organisms ranging from 3 to 30 µm in diameter. They manifest as thick-walled, spherical bodies with no budding.…”

Skin Infections

“…1016 They usually have a slowly progressive course with no tendency to self-heal. 1030 Usually, there is a chronic granulomatous reaction throughout the dermis, which may also involve the subcutaneous tissue, associated with a variable admixture of lymphocytes, neutrophils, plasma cells, and occasional eosinophils. 1016,1020,[1023][1024][1025][1026][1027][1028] Lesions resembling herpes, eczema, subcutaneous mycoses, and pyoderma gangrenosum have also been described.…”

“…1017 The epidermis can exhibit hyperkeratosis, focal parakeratosis, and pseudoepitheliomatous hyperplasia. 1016,1020,1021,1023,[1030][1031][1032] Prototheca species are spherical, unicellular organisms ranging from 3 to 30 µm in diameter. They manifest as thick-walled, spherical bodies with no budding.…”