Noncovalent interactions of antitumor cycloplatinated complexes containing trifluoroacetate ligands as the leaving group with bovine serum albumin. Implications for drug design

Abstract

The cytotoxicity and biomolecular interactions of monofunctional cycloplatinated(ii) complexes, [Pt(C^N)(OCOCF3)(SMe2)], involving trifluoroacetate ligands as the leaving group are investigated by using different spectrophotometric techniques.