Nonanimal Stabilized Hyaluronic Acid for Tissue Augmentation of the Dorsal Hands: A Prospective Study on 38 Patients

Abstract

Background Often ignored, hands are one of the most telltale signs of aging. This prospective study was initiated to evaluate the effect of subcutaneous hyaluronic acid (HA) injections in aging hands, with special attention to complications and long-term outcomes. Methods Between January 2010 and December 2010, a total of 38 patients with skin phototypes II-IV and between 58 and 76 years old were treated with HA injection for aging hands. The quantity of injection never exceeded 1.0-1.5 ml HA per hand. A clinical follow-up was performed at 2 weeks, 4 weeks, 3 months, and 6 months after injection. Complications were reviewed for the whole series. At the first follow-up, 2 weeks after the procedure, ultrasound was carried out to determine if additional filling material was required. At each follow-up, patients were asked to fill out a satisfaction questionnaire. Results Nine patients developed slight ecchymosis that disappeared after 1 week. No other complications were seen in the series. Pain during the injection and discomfort after the procedure were minimal. At the 2-week follow-up, after ultrasound control, nine patients received a complementary injection. At each follow-up, overall patient satisfaction was high and was validated by clearance of rhytids, veins, bony prominences, and dermal and subcutaneous atrophy. Conclusion Skin revitalization with injectable HA can improve the clinical appearance of the back of the hands. However, this therapy requires knowledge of the possible complications and their remediation as well as knowledge and respect of injected doses. Moreover, despite excellent results at each follow-up, the results of our series are not as good after 6 months, and a longer follow-up would be needed to determine if this procedure provides long-lasting benefit.

Η Επίδραση Της Εξωγενούς Χορήγησης Υαλουρονικού Οξέος Στην Επούλωση Χειρουργικών Τομών

“…Οι περιοχές που μπορούν να διορθωθούν αφορούν κυρίως στο μέσο τμήμα του προσώπου, χωρίς όμως να περιορίζονται σε αυτό.Αντίθετα, αποτελεί αντένδειξη η εφαρμογή υαλουρονικού οξέος σε μη διατατές ουλές, στην περιοχή του λαιμού, καθώς και σε θέσεις όπου έχει προηγηθεί εφαρμογή μόνιμων ή άγνωστων ενέσιμων υλικών, τα οποία είναι ακόμη ψηλαφητά117 .Εκτός προσώπου, σκευάσματα υαλουρονικού οξέος χρησιμοποιούνται για την αναζωογόνηση της ραχιαίας επιφάνειας των χεριών. Στην περίπτωση αυτή, το υλικό ενίεται κάτω από το χόριο, προσθέτοντας το έλλειμμα, εξαιτίας γήρανσης, όγκου, και ταυτόχρονα συμπιέζοντας της φλέβες της ραχιαίας επιφάνειας, συμβάλλοντας στην «κάλυψή» τους125,126 . Το υαλουρονικό οξύ έχει προταθεί και χρησιμοποιηθεί ως εναλλακτικό των ενθεμάτων για την αύξηση του όγκου του μαστού.…”