Non-volatile oxylipins can render some diatom blooms more toxic for copepod reproduction

Ianora, Adrianna; Bastianini, Mauro; Carotenuto, Ylenia; Casotti, Raffaella; Roncalli, Vittoria; Miralto, Antonio; Romano, Giovanna; Gerecht, Andrea; Fontana, Angelo; Turner, Jefferson T.

doi:10.1016/j.hal.2015.02.003

Cited by 30 publications

(23 citation statements)

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“…In general, the higher the quantity of oxylipins and FAHs in the benthic species, the higher the number of abnormal plutei spawned (Figure 5a,b). In agreement with the results on planktonic copepods [46,50], the detrimental response of sea urchin embryos seems to be due to an accumulation of LOX-derived metabolites and does not depend on a specific class of oxylipins.…”

Section: Discussionsupporting

confidence: 89%

Lipoxygenase Pathways in Diatoms: Occurrence and Correlation with Grazer Toxicity in Four Benthic Species

et al. 2020

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Oxygenated derivatives of fatty acids, collectively called oxylipins, are a highly diverse family of lipoxygenase (LOX) products well described in planktonic diatoms. Here we report the first investigation of these molecules in four benthic diatoms, Cylindrotheca closterium, Nanofrustulum shiloi, Cocconeis scutellum, and Diploneis sp. isolated from the leaves of the seagrass Posidonia oceanica from the Gulf of Naples. Analysis by hyphenated MS techniques revealed that C. closterium, N. shiloi, and C. scutellum produce several polyunsaturated aldehydes (PUAs) and linear oxygenated fatty acids (LOFAs) related to the products of LOX pathways in planktonic species. Diploneis sp. also produced other unidentified fatty acid derivatives that are not related to LOX metabolism. The levels and composition of oxylipins in the benthic species match their negative effects on the reproductive success in the sea urchin Paracentrotus lividus. In agreement with this correlation, the most toxic species N. shiloi revealed the same LOX pathways of Skeletonema marinoi and Thalassiosira rotula, two bloom-forming planktonic diatoms that affect copepod reproduction. Overall, our data highlight for the first time a major role of oxylipins, namely LOFAs, as info-chemicals for benthic diatoms, and open new perspectives in the study of the structuring of benthic communities.

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Section: Discussionsupporting

confidence: 89%

Lipoxygenase Pathways in Diatoms: Occurrence and Correlation with Grazer Toxicity in Four Benthic Species

et al. 2020

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“…Большинство видов диато-мей продуцируют по меньшей мере 2 класса оксилипинов, полиненасыщенные альдегиды и нелетучие оксилипины. Эти компоненты могут действовать как сдерживающий консументов фактор, нарушая их репродуктивный процесс [38], повышая смертность самок [21], уменьшая биомассу [14], повреждая ранние личиночные стадии развития (в экспериментах) [14,17,24,57,72].…”

Section: сигналинг в водных экосистемахunclassified

Современные Тенденции Развития Биологии Водных Экосистем

Likhoshvai

2017

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Охарактеризованы новые направления океанологии, сформированные в последние несколько лет бла-годаря внедрению в практику современных методов получения и обработки данных. Это методы мас-сового секвенирования, «омики» и биоинформационные методы хранения и анализа данных. Выяв-ление биологически активных веществ в водной среде и результаты лабораторных экспериментов по-казывают, что существует молекулярное взаимодействие (сигналинг) как на уровне популяционных и межвидовых отношений между микроорганизмами, так и на уровне их трофических связей. «От мо-лекул к экосистеме» -так охарактеризовано актуальное направление биологии морских экосистем. Объединение и анализ огромных массивов данных, включая полученные с помощью космических съё-мок и «облачных» технологий, сформировали новое направление экоинформатики, которое примени-тельно к водным экосистемам позволяет приблизиться к пониманию их структурно-функциональной организации в целом.Ключевые слова: биология водных экосистем, «омики», большие данные, сигналинг

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“…Chemical analyses of mono-algal cultures has revealed strictly LOX species-specificity [ 30 ], where the most common pathway shared by different genera of diatoms rely on a 15 S -LOX activity, and a minor group of oxylipins are the products of 5-LOX, 8-LOX, 9 S -LOX, 11-LOX, 12-LOX and 14-LOX [ 19 , 20 , 22 , 30 , 31 , 32 , 33 , 34 ] activity, depending on the specific regiochemistry of carbon oxidation. Oxylipin quantification and variation in time and space has been evaluated in field studies [ 35 , 36 , 37 , 38 , 39 , 40 , 41 ]. A recent survey demonstrated that oxylipin pathways in diatoms were mostly based on the oxygenation of hexadecatrienoic, eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids, and, within phytoplankton communities, these secondary metabolites largely derived from diatoms [ 42 ].…”

Section: Introductionmentioning

confidence: 99%

Multiple Roles of Diatom-Derived Oxylipins within Marine Environments and Their Potential Biotechnological Applications

et al. 2020

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The chemical ecology of marine diatoms has been the subject of several studies in the last decades, due to the discovery of oxylipins with multiple simultaneous functions including roles in chemical defence (antipredator, allelopathic and antibacterial compounds) and/or cell-to-cell signalling. Diatoms represent a fundamental compartment of marine ecosystems because they contribute to about 45% of global primary production even if they represent only 1% of the Earth’s photosynthetic biomass. The discovery that they produce several toxic metabolites deriving from the oxidation of polyunsaturated fatty acids, known as oxylipins, has changed our perspectives about secondary metabolites shaping plant–plant and plant–animal interactions in the oceans. More recently, their possible biotechnological potential has been evaluated, with promising results on their potential as anticancer compounds. Here, we focus on some recent findings in this field obtained in the last decade, investigating the role of diatom oxylipins in cell-to-cell communication and their negative impact on marine biota. Moreover, we also explore and discuss the possible biotechnological applications of diatom oxylipins.

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Non-volatile oxylipins can render some diatom blooms more toxic for copepod reproduction

Cited by 30 publications

References 55 publications

Lipoxygenase Pathways in Diatoms: Occurrence and Correlation with Grazer Toxicity in Four Benthic Species

Lipoxygenase Pathways in Diatoms: Occurrence and Correlation with Grazer Toxicity in Four Benthic Species

Современные Тенденции Развития Биологии Водных Экосистем

Multiple Roles of Diatom-Derived Oxylipins within Marine Environments and Their Potential Biotechnological Applications

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