Non-18F-FDG PET/CT in the management of patients affected by HNC

Abstract

PET/computed tomography with F-fluorodeoxyglucose is considered a powerful molecular imaging technique that can provide useful information in the management of patients affected by head and neck cancer. However, misleading findings have been reported because of nonspecific uptake caused by peritumoural inflammation and physiologic changes in nonmalignant tissues in the head and neck region. More specific β-emitting tracers have been introduced that can track other pathological processes. We aimed to review the existing literature performing the search until June 2015 on non-F-fluorodeoxyglucose PET tracers in head and neck cancer to highlight their role in clinical practice.

PET and MRI guided adaptive radiotherapy: Rational, feasibility and benefit

“…Methionine is an essential amino-acid whose increased consumption is often correlated with cell proliferation. 11C-methionine PET/CT shows divergent results compared to FDG PET/CT [8].…”