2003
DOI: 10.1001/archderm.139.9.1157
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Nodular Amyloidosis

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Cited by 82 publications
(36 citation statements)
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“…The nodules, which usually range from 1 to 3 cm in diameter, have a typically waxy, tumefactive appearance. Patients that are between 50 and 60 years old (mean age: 55 years) are most often affected with no sex predilection5,7.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The nodules, which usually range from 1 to 3 cm in diameter, have a typically waxy, tumefactive appearance. Patients that are between 50 and 60 years old (mean age: 55 years) are most often affected with no sex predilection5,7.…”
Section: Discussionmentioning
confidence: 99%
“…The dermal amyloid L protein is derived from immunoglobulin light chains produced by locally infiltrated plasma cells4,7,12. The precise cause of localized infiltration of plasma cells is unknown.…”
Section: Discussionmentioning
confidence: 99%
“…Nevertheless, in our opinion, close follow-up for progression to systemic amyloidosis or autoimmune disease is indicated because recent studies show that systemic progression of primary nodular amyloidosis is near 10%. [11][12][13] The pathogenesis of amyloid elastosis remains unknown. It has been suggested that amyloid P component, which is closely associated with elastic fibers in normal skin, could drive the deposition of serum amyloid antigen around elastic fibers in patients with systemic amyloidosis.…”
Section: Discussionmentioning
confidence: 99%
“…In the latter two types, amyloid fibrils accumulate in the papillary dermis. An uncommon form of amyloidosis may affect the subcutis, dermis and vascular walls, causing local plasma cell dyscrasia (35,36). Nodular amyloidosis has a higher relapse rate compared with the other forms.…”
Section: Discussionmentioning
confidence: 99%