5-Sulphonamido-8-quinolinol reacts with cinnamonitrile derivatives in the presence of a basic catalyst to give pyrano[3,2-h]quinoline sulphonamide derivatives (8a4-13a4). The reaction of S, , , 9, with some reagents such as acetic anhydride, acetic anhydride/pyridine mixture, formamide and formic acid/ formamide mixture gave the fused heterotetracyclic systems pyrimido-[4, 5' : 6, 5]pyrano[3, 2-h] quinoline sulphonamide derivatives. The structures of all newly synthesized compounds were confirmed by elemental…
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