Biochemical Pharmacology volume 82, issue 8, P820-827 2011 DOI: 10.1016/j.bcp.2011.06.021 View full text
Nolan R. Campbell, Catarina C. Fernandes, Danielle John, Adrian F. Lozada, Darwin K. Berg

Abstract: The hippocampus is one of only two regions in the adult brain where neurons are generated in significant numbers throughout the lifetime of the animal. Numerous studies have demonstrated that these adult-born neurons are essential for optimal cognitive function with unimpaired memory formation and retrieval. The extent to which adult-born neurons survive through an early “critical period” and become integrated into functional networks has been shown to depend on the richness of stimulation they receive during…

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