2015
DOI: 10.1016/j.alcohol.2015.03.002
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Clinical studies demonstrate frequent co-existence of nicotine and alcohol abuse and suggest that this may result, in part, from the ready access to and intake of fat-rich diets. Whereas animal studies show that high-fat diet intake in adults can enhance the consumption of either nicotine or ethanol and that maternal consumption of a fat-rich diet during pregnancy increases operant responding for nicotine in offspring, little is known about the impact of dietary fat on the co-abuse of these two drugs. The goal… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
7
0

Year Published

2017
2017
2023
2023

Publication Types

Select...
5
1

Relationship

0
6

Authors

Journals

citations
Cited by 9 publications
(7 citation statements)
references
References 117 publications
(158 reference statements)
0
7
0
Order By: Relevance
“…[24, 26, 34, 35]. PR sessions ended after two hrs or 20 min without a response, whichever occurred first [26, 28, 29, 33, 36]. All rats then had access to saline on a PR schedule for five sessions for comparison.…”
Section: Methodsmentioning
confidence: 99%
“…[24, 26, 34, 35]. PR sessions ended after two hrs or 20 min without a response, whichever occurred first [26, 28, 29, 33, 36]. All rats then had access to saline on a PR schedule for five sessions for comparison.…”
Section: Methodsmentioning
confidence: 99%
“…Anxiety-related effects were mixed, with offspring from the pregestation dietary intervention group (mothers returned to a healthy diet) showing partial recovery (Rodriguez et al, 2012). Substance-use related behavioral effects of prenatal high-fat exposure have been documented in rats (Karatayev et al, 2015). Exposed offspring engaged in more extensive nicotine and ethanol self-administration, relevant to temperament because of associated impulsivity/behavioral undercontrol.…”
Section: Substance Use and Effects Of Psychotropic Medicationmentioning
confidence: 99%
“…Human research indicates that both obesity and the consumption of an HFD increases total food consumption and the risk of alcohol [30,31] and nicotine addictions [32]. Recently, an increasing number of preclinical studies focused mainly on maternal HFDs have proven that nutrition may predispose offspring to an increased intake of palatable food [10,11,33], drinking alcohol [16,34,35], nicotine [14], or simultaneous ethanol and nicotine [13] self-administration. In this paper, a series of behavioral tests using an animal model of intravenous cocaine self-administration to determine the female offspring phenotype after exposure to modified maternal diets were performed.…”
Section: Discussionmentioning
confidence: 99%
“…In fact, exposure to excessive or insufficient amounts of macronutrients (fats, sugars, proteins) can lead to morphological, molecular, and functional changes in the brains of offspring, predisposing them to the occurrence of behavioral disorders and mental diseases, such as increased impulsiveness, depression, or anxiety, which further predispose them to the risk of developing substance use disorders later in life [5][6][7][8][9]. A maternal diet rich in fat provokes increased consumption and preference for palatable but unhealthy food in offspring [10][11][12], increased nicotine and ethanol self-administration [13,14], and disturbed behavioral reactions in animals regarding the administration of psychostimulant substances (reduced locomotor activity and amphetamine-induced behavioral sensitization) [15]. In turn, a maternal diet rich in fructose or sucrose induces an increase in the amount of alcohol consumed by the offspring [16].…”
Section: Introductionmentioning
confidence: 99%