News About Influenza B Drug Resistance That Cannot Be Ignored

Antiviral Oseltamivir Is not Removed or Degraded in Normal Sewage Water Treatment: Implications for Development of Resistance by Influenza A Virus

“…This raises the all-important question as to whether or not such a risk should be taken, or if a more restricted use of these agents should be advocated? This is an opinion shared by other researchers [28], and we would like to add that the effects of pharmaceuticals continuously released into the environment should not be underestimated and certainly investigated carefully before widespread use of a drug is encouraged.…”

Meeting Report: Risk Assessment of Tamiflu Use Under Pandemic Conditions

“…Greater than 90% of the prescriptions for seasonal influenza in Japan are for OE-P (Moscona and McKimm-Breschkin 2007). Sewage works in Japan have been processing OC from 5–10% population treatment per annum for > 4 years.…”

Persistent Infection of Drug-resistant Influenza A Virus during Chemotherapy for Malignant Lymphoma

“…However, drug-resistant viral strains generally have a less proliferative capacity than susceptible ones (21)(22)(23)(24)(25), so it might not have been detected even if a surveillance assay had been performed earlier. Although it is difficult to identify specific symptoms characteristic of the drug-resistant influenza virus in the present case, the lack of any respiratory tract symptoms per se might be a typical clinical feature of this strain.…”