Newcastle Disease Encephalomyelitis in Cats

Spinal Myoclonus

“…As mentioned by Luttrell et al (1959) spinal myoclonus pro duced in cats by infection with Newcastle disease virus could be influenced by auditive stimuli. Repeatedly it was described in the clinical literature that the spinal myoclonus disappears during sleep and can be activated by mental distress, i.e.…”

“…Luttrell et al (1959) and Luttrell and Bang (1957) produced myoclonus in cats by infection of the spinal cord with the Newcastle disease virus. The myoclonic symp toms first appeared in the muscles supplied by the locally infected segments of spinal cord.…”

Spinal Myoclonus

“…As mentioned by Luttrell et al (1959) spinal myoclonus pro duced in cats by infection with Newcastle disease virus could be influenced by auditive stimuli. Repeatedly it was described in the clinical literature that the spinal myoclonus disappears during sleep and can be activated by mental distress, i.e.…”

“…Luttrell et al (1959) and Luttrell and Bang (1957) produced myoclonus in cats by infection of the spinal cord with the Newcastle disease virus. The myoclonic symp toms first appeared in the muscles supplied by the locally infected segments of spinal cord.…”

Spinal myoclonus: a rare presentation of cervical myelopathy

“…The inappropriate function of the SSG is reflected on the EMG trace as muscle contractions in the range of usually 1–3 Hz lasting between +50 and −500 ms 34–37. Experimental animal studies have launched the discussion on the pathophysiological mechanisms responsible for SSG dysfunction, through iatrogenically induced spinal cord lesions and infections,15 38–40 with deficiencies in inhibitory neurotransmitters and vitamin B 12 supplementing the key hypotheses 41. This was explored further in the late 1980s, demonstrating that neuronal destruction within the grey matter of the spinal cord at the involved segments could precipitate myoclonal movements 42 43.…”

Stimulus-sensitive spinal myoclonus.

“…Auditory stimuli enhanced myoclonus in cats inoculated with Newcastle Disease virus. 15 Leigh et al'9 have recently described a patient with progressive muscular rigidity associated with reflex myoclonus of axial and leg muscles which occurred both spontaneously and in response to muscle stretch of the head and neck and to light touch to the perioral region. As in segmental myoclonus the jerking was rhythmic at times and there was evidence of a focal lesion, in this case an atrophic process affecting the lower brainstem and cerebellum.…”

Spinal Myoclonus

“…As mentioned by Luttrell et al (1959) spinal myoclonus pro duced in cats by infection with Newcastle disease virus could be influenced by auditive stimuli. Repeatedly it was described in the clinical literature that the spinal myoclonus disappears during sleep and can be activated by mental distress, i.e.…”

“…Luttrell et al (1959) and Luttrell and Bang (1957) produced myoclonus in cats by infection of the spinal cord with the Newcastle disease virus. The myoclonic symp toms first appeared in the muscles supplied by the locally infected segments of spinal cord.…”

Spinal myoclonus: a rare presentation of cervical myelopathy

“…The inappropriate function of the SSG is reflected on the EMG trace as muscle contractions in the range of usually 1–3 Hz lasting between +50 and −500 ms 34–37. Experimental animal studies have launched the discussion on the pathophysiological mechanisms responsible for SSG dysfunction, through iatrogenically induced spinal cord lesions and infections,15 38–40 with deficiencies in inhibitory neurotransmitters and vitamin B 12 supplementing the key hypotheses 41. This was explored further in the late 1980s, demonstrating that neuronal destruction within the grey matter of the spinal cord at the involved segments could precipitate myoclonal movements 42 43.…”

Stimulus-sensitive spinal myoclonus.

“…Auditory stimuli enhanced myoclonus in cats inoculated with Newcastle Disease virus. 15 Leigh et al'9 have recently described a patient with progressive muscular rigidity associated with reflex myoclonus of axial and leg muscles which occurred both spontaneously and in response to muscle stretch of the head and neck and to light touch to the perioral region. As in segmental myoclonus the jerking was rhythmic at times and there was evidence of a focal lesion, in this case an atrophic process affecting the lower brainstem and cerebellum.…”

Spinal Myoclonus

“…As mentioned by Luttrell et al (1959) spinal myoclonus pro duced in cats by infection with Newcastle disease virus could be influenced by auditive stimuli. Repeatedly it was described in the clinical literature that the spinal myoclonus disappears during sleep and can be activated by mental distress, i.e.…”

“…Luttrell et al (1959) and Luttrell and Bang (1957) produced myoclonus in cats by infection of the spinal cord with the Newcastle disease virus. The myoclonic symp toms first appeared in the muscles supplied by the locally infected segments of spinal cord.…”

Spinal myoclonus: a rare presentation of cervical myelopathy

“…The inappropriate function of the SSG is reflected on the EMG trace as muscle contractions in the range of usually 1–3 Hz lasting between +50 and −500 ms 34–37. Experimental animal studies have launched the discussion on the pathophysiological mechanisms responsible for SSG dysfunction, through iatrogenically induced spinal cord lesions and infections,15 38–40 with deficiencies in inhibitory neurotransmitters and vitamin B 12 supplementing the key hypotheses 41. This was explored further in the late 1980s, demonstrating that neuronal destruction within the grey matter of the spinal cord at the involved segments could precipitate myoclonal movements 42 43.…”

Stimulus-sensitive spinal myoclonus.

“…Auditory stimuli enhanced myoclonus in cats inoculated with Newcastle Disease virus. 15 Leigh et al'9 have recently described a patient with progressive muscular rigidity associated with reflex myoclonus of axial and leg muscles which occurred both spontaneously and in response to muscle stretch of the head and neck and to light touch to the perioral region. As in segmental myoclonus the jerking was rhythmic at times and there was evidence of a focal lesion, in this case an atrophic process affecting the lower brainstem and cerebellum.…”