The paper discusses Siberian transport infrastructure formation in the context of the country's history. The construction of new train routes, namely Transsib and BAM, led to the rapid economic development of the territories. Siberian vast areas did not militate against the construction of oil and gas pipelines as a precursor of the complex intergovernmental One Belt, One Road initiative. Solving problems in infrastructural development will lead to steady growth and dynamics of economic advancement of Russia and neighboring countries.