New Radiopharmaceuticals Based on Prostate-Specific Inhibitors of Membrane Antigen for Diagnostics and Therapy of Metastatic Prostate Cancer

Op, Vlasova; German, K. É.; Vv, Krilov; Vm, Petriev; Nb, Epstein

doi:10.15690/vramn.v70i3.1334

Cited by 2 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…ПСМА -мембранный гликопротеин, активно экспрессирующийся клетками РПЖ (в 100-1000 раз больше по сравнению с нормальной тканью предста-тельной железы и другими органами). Экспрессия ПСМА возрастает при метастатическом кастрационно-резистентном РПЖ, что делает его перспективным мар-кером при радионуклидной диагностике [13,17,18].…”

Section: диагностика и лечение опухолей мочеполовой системы рак предunclassified

“…В последнее время в ряде стран Европы и США в клиническую практику активно внедряются методы, основанные на использовании изотопа галлия ( 68 Ga), а также ПЭТ с простатическим специфическим мем-бранным антигеном (ПСМА) [11][12][13], но они доступ-ны не во всех клиниках из-за высокой стоимости ис-следования. В России на сегодняшний день единственными доступными являются методики, основанные на использовании холина и 11 С-глюкозы.…”

Section: Introductionunclassified

See 1 more Smart Citation

Methods for the diagnosis and treatment of oligometastases in patients with prostate cancer and progressive disease after radical treatment

Алексеев¹,

Нюшко²,

Krasheninnikov³

et al. 2016

Cancer Urology

View full text Add to dashboard Cite

Section: диагностика и лечение опухолей мочеполовой системы рак предunclassified

Section: Introductionunclassified

Methods for the diagnosis and treatment of oligometastases in patients with prostate cancer and progressive disease after radical treatment

Алексеев¹,

Нюшко²,

Krasheninnikov³

et al. 2016

Cancer Urology

View full text Add to dashboard Cite

Application of radiolabeled ligands to the prostate-specific membrane antigen for determine localization of biochemical recurrence of prostate cancer by PET/CT (literature review)

Leontyev

Рубцова

Khalimon

et al. 2018

Medicinskaâ vizualizaciâ

View full text Add to dashboard Cite

In present days positron emission tomography combined with X-ray computed tomography (PET/CT) is a highly informative, actively developing method of visualization in oncology, and in particular in oncourology. It is widely used to determine the localization of biochemical recurrence (BR) of prostate cancer (PCa). This survey article presents modern trends and prospects of the development of PET visualization of BR of PCa. It shows the diagnostic capabilities of PET/CT with various radiopharmaceuticals, including ligands for prostate-specific membrane antigen (PSMA), their main advantages and disadvantages. Brief historical information, the evolution of radiopharmaceuticals based on ligands to PSMA as the most promising group of radiopharmaceuticals are provided in the article. The biochemical basis of visualization, the main difficulties and possible errors in the interpretation of data, as well as the ways of overcoming them proposed by the researchers are highlighted.

show abstract

New Radiopharmaceuticals Based on Prostate-Specific Inhibitors of Membrane Antigen for Diagnostics and Therapy of Metastatic Prostate Cancer

Cited by 2 publications

References 10 publications

Methods for the diagnosis and treatment of oligometastases in patients with prostate cancer and progressive disease after radical treatment

Methods for the diagnosis and treatment of oligometastases in patients with prostate cancer and progressive disease after radical treatment

Application of radiolabeled ligands to the prostate-specific membrane antigen for determine localization of biochemical recurrence of prostate cancer by PET/CT (literature review)

Contact Info

Product

Resources

About