2007
DOI: 10.1002/jbm.b.30859
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Abstract: The inflammatory and fibrotic intensity of a foreign body reaction largely depends on the porosity of the implanted material. Furthermore, the size of the pore and its geometry define the capability to allow tissue ingrowth. We present an image analysis system, which allows objectifying in two dimensions the pores' structure and geometry of textile fabrics, that are used to reinforce the abdominal wall or pelvic floor. The porosity of the textile is measured at four samples with differences in structure. The p… Show more

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Cited by 74 publications
(69 citation statements)
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“…Of course, pore size has an effect on sealant penetration. Mü hl et al [11] showed that pore size and geometry also define the conditions for tissue in-growth and coined the term ''effective porosity,'' which takes into account the intensity of the foreign body reaction to the mesh and the ensuing proliferation and decrease in pore size. Porosity and hydrophobicity of the mesh affect the intensity of the foreign body reaction.…”
Section: Discussionmentioning
confidence: 99%
“…Of course, pore size has an effect on sealant penetration. Mü hl et al [11] showed that pore size and geometry also define the conditions for tissue in-growth and coined the term ''effective porosity,'' which takes into account the intensity of the foreign body reaction to the mesh and the ensuing proliferation and decrease in pore size. Porosity and hydrophobicity of the mesh affect the intensity of the foreign body reaction.…”
Section: Discussionmentioning
confidence: 99%
“…The implants could be made of polypropylene (PP), polyethylene terephthalate (PET), expanded polytetrafluoroethylene (ePTFE), polyvinylidene fluoride (PVDF), and absorbable materials, such as polylactide (PLA), polyglycolic acid (PGA), polycaprolactone (PCL) and polydioxanone (PDO) [16]. In studies PVDF showed highly effective porosity [17], stability [18], less foreign body reaction [19] and superior ageing resistance [20]. Prof. Dr. W. Jager used polyvinylidene fluoride tape and the first results demonstrated, that urge and mixed urinary incontinence could be treated not only prescribing medication, but also by the surgery.…”
Section: Discussionmentioning
confidence: 99%
“…This 'bridging' leaves no space for further tissue ingrowth [12,13]. Embedding of the implant into such a scar plate leads to a loss of elasticity and may consecutively support the shrinkage of the prosthesis [93]. Apart from the relevance for the in vivo host reaction, the importance of pore size is demonstrated in the field of tissue engineering in vitro as well [94,95].…”
Section: Pore Sizementioning
confidence: 98%
“…They concluded that, considering the pore as a polymer-free space for future tissue ingrowth, the obligate foreign body granuloma, which wraps the filaments, has to be considered as well. Correspondingly, only pores with a diameter of >1 mm are regarded as appropriate [93] and contributes to the effective porosity of a mesh structure. In a joint attempt of the manufacturers for grouping all the different mesh implants, all meshes with a preserved effective porosity of >0% are regarded as large pore prosthesis, whereas structures with an effective porosity of 0% are defined as small pore meshes.…”
Section: Pore Sizementioning
confidence: 99%