New Insights Into Idiopathic Infantile Arterial Calcinosis

Prenatal diagnosis of idiopathic infantile arterial calcification with hydrops fetalis

“…It has been reported that IIAC is an autosomal recessive disorder6, 7. This is consistent with the cases described here.…”

Antenatal diagnosis of idiopathic infantile arterial calcification (IIAC): a single centre experience and review of the literature

“…Few articles have reported cerebral artery involvement as in our fourth case and in the recipient twin described above [25]. Calcification of the cerebral arteries has been described in four cases [32][33][34][35], the earliest reported case in 1948 [33]. Glatz et al 2006 [3] described a case of rare focal parenchymal microcalcifications in the area of the corpus striatum, internal capsule and choroid plexus on postmortem.…”

Idiopathic infantile arterial calcification: Two case reports, a review of the literature and a role for cardiac transplantation

“…Importantly, calcification of the coronary arteries is estimated to occur in 85% of cases (35) and cardiac failure is the typical cause of death. Cerebral arteries are usually spared, although isolated cases report their involvement (10, 31, 33), including the single vessel seen in case one of our series. The histopathologic findings in IIAC are importantly distinguishable from atherosclerosis, where lipid is present in the intima and Monckeberg's sclerosis, which primarily affects the medial layer (2, 3).…”