2019
DOI: 10.1155/2019/4598167
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Abstract: Aging is a progressive disease affecting around 900 million people worldwide, and in recent years, the mechanism of aging and aging-related diseases has been well studied. Treatments for aging-related diseases have also made progress. For the long-term treatment of aging-related diseases, herbal medicine is particularly suitable for drug discovery. In this review, we discuss cellular and molecular mechanisms of aging and aging-related diseases, including oxidative stress, inflammatory response, autophagy and e… Show more

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Cited by 66 publications
(43 citation statements)
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References 252 publications
(244 reference statements)
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“…One popular plant is Rhodiola rosea L. (golden root, roseroot; synonym Sedum roseum (L.) Scop., Crassulaceae family), a medicinal species with a disjunct distribution in Eurasia and known as a medical remedy [1]. The roots and rhizome of R. rosea are the source of numerous metabolites, like acyclic alcohol derivatives, benzyl glucosides, phenols, hydroxycinnamates, gallotannins, flavonoids, catechins, procyanidins, and terpenes [2], with a diversity of bioactivities as antioxidant [3], anticancer [4], antidiabetic [5], antidepressant, neuroprotective [6], anti-inflammatory [7], and adaptogenic [8] agents. The main reserves of R. rosea are concentrated in Siberian regions such as Altai, Western Sayans, and Tuva [9].…”
Section: Introductionmentioning
confidence: 99%
“…One popular plant is Rhodiola rosea L. (golden root, roseroot; synonym Sedum roseum (L.) Scop., Crassulaceae family), a medicinal species with a disjunct distribution in Eurasia and known as a medical remedy [1]. The roots and rhizome of R. rosea are the source of numerous metabolites, like acyclic alcohol derivatives, benzyl glucosides, phenols, hydroxycinnamates, gallotannins, flavonoids, catechins, procyanidins, and terpenes [2], with a diversity of bioactivities as antioxidant [3], anticancer [4], antidiabetic [5], antidepressant, neuroprotective [6], anti-inflammatory [7], and adaptogenic [8] agents. The main reserves of R. rosea are concentrated in Siberian regions such as Altai, Western Sayans, and Tuva [9].…”
Section: Introductionmentioning
confidence: 99%
“…Aging, characterized by a progressive loss of physiological integrity, leads to impaired functioning and increased vulnerability to death [ 1 ]. It is highly related to the development of various diseases, such as arteriosclerotic cardiovascular disease, diabetes, Alzheimer's disease, and macular degeneration [ 2 ]. Increasingly, researchers are keen to find effective compounds that can promote healthy aging and extend lifespan.…”
Section: Introductionmentioning
confidence: 99%
“…The study nds that the chemical composition of EGb is complex, including avonoids, lactones, polypentenols, and alkyl phenolic acids, organic acids, steroids, trace elements, etc [10]. EGb preparation is a relatively successful case of plant medicine developed by modern science and technology, and occupies an important position in the eld of anti-aging and clinical medication for cardiovascular and cerebrovascular diseases [9,11]. Previous studies have shown that EGb has certain e cacy in the prevention and treatment of age-related diseases [9,[12][13][14].…”
Section: Introductionmentioning
confidence: 99%