New generation quantum dots as contrast agent in imaging

Thondavada, Niranjan; Chokkareddy, Rajasekhar; Naidu, Nuthalapati Venkatasubba; Redhi, Gan G.

doi:10.1016/b978-0-12-817923-9.00015-8

Cited by 6 publications

(2 citation statements)

References 89 publications

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“…184 Importantly, they can be combined with fluorescent imaging 193 or additional techniques. Fluorescent NPs that avoid spectral overlap, such as quantum dots 194,195 or carbon dots 196 harbor great potential and are compatible with magnetic resonance imaging (MRI) techniques, when doped with specific elements such Gd(III). 197 Alternatively, magnetic NPs can be used as contrast agents, offering non-invasive deep imaging with low background signal generation not only for MRI 198 but also for magnetic particle imaging (MPI).…”

Section: Nanoparticle-based Characterization Of In Vitro Lung Modelsmentioning

confidence: 99%

Dynamic 3D in vitro lung models: applications of inorganic nanoparticles for model development and characterization

Fallert,

Urigoitia-Asua,

Cipitria

et al. 2024

Nanoscale

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Section: Nanoparticle-based Characterization Of In Vitro Lung Modelsmentioning

confidence: 99%

Dynamic 3D in vitro lung models: applications of inorganic nanoparticles for model development and characterization

Fallert,

Urigoitia-Asua,

Cipitria

et al. 2024

Nanoscale

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“…However, uncoated CQD materials have the potential to generate cadmium ions, leading to toxicity in cells, and it is therefore essential to apply biocompatible coating substances to cover their surfaces. For instance, a CdSe and CdS nanocrystal enclosed in a silica shell in an aqueous buffer can emit green (2-nm core) and red (4-nm core) fluorescence [2]. Poly (N-isopropylacrylamide)-encapsulated CdTe nanospheres exhibit good colloidal stability and strong green luminescence [3], and liposomal encapsulated CdSe/CdZnS emit red light [4].…”

Section: Introductionmentioning

confidence: 99%

Green synthesis of carbon dots from mangosteen peel for fluorescent cancer cells

AMLOY,

LUKPRANG,

LERTWORAPREECHA

et al. 2024

J Met Mater Miner

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Recently, carbon dots (CDs) have received significant attention owing to their outstanding optical properties, good solubility, and low toxicity. In this research, CDs were synthesized by a hydrothermal method based on an environmentally friendly and straightforward strategy, using only mangosteen peel and deionized water. The synthesized CDs had an average size of 3.09 ± 0.38 nm. The absorbance spectrum peak for the CDs was seen at 282 nm, and the central wavelength of fluorescence emission was observed at 433 nm under an excitation wavelength of 355 nm. An aqueous solution of CDs exhibited bright green fluorescence when observed with the naked eye under UV irradiation. Both Fourier transform infrared and X-ray photoelectron spectroscope measurements were taken to determine the elemental compositions of the organic substance functional groups on the surface of the CD, such as hydroxyl, carboxyl, and carbonyl groups. These functional groups originate the different emission centers leading to multicolor fluorescent emissions. Furthermore, the synthesized CDs were found to have good biocompatibility with organic and biological materials. The remarkable properties of CDs, including their nanoscale dimensions, strong multicolor fluorescent emissions, non-toxicity, and excellent cell compatibility, could effectively permeate the cell membrane, cytoplasm, and nucleus and provide fluorescence emission. This suggests a significant potential for CDs in fluorescent cell staining applications. Finally, the CDs were used as a fluorescent dye for human colon cancer cells, as they exhibited excellent fluorescence for cell staining.

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