2017
DOI: 10.1016/j.jaad.2016.10.048
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New discoveries in the pathogenesis and classification of vitiligo

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Cited by 324 publications
(357 citation statements)
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“…Also note that the clinically stable, central, nonpigmented areas were devoid of pigmented cells. This observation reflects the histopathological finding of a complete loss of epidermal pigmentation and absence of melanocytes at the basal layer in well‐established lesional achromic skin (Rodrigues, Ezzedine, Hamzavi, Pandya, & Harris, ). In all vitiliginous lesions examined with FAV, the erythrocytes within the capillaries of the papillary dermis were the only visible structures (Figure a).…”
supporting
confidence: 81%
“…Also note that the clinically stable, central, nonpigmented areas were devoid of pigmented cells. This observation reflects the histopathological finding of a complete loss of epidermal pigmentation and absence of melanocytes at the basal layer in well‐established lesional achromic skin (Rodrigues, Ezzedine, Hamzavi, Pandya, & Harris, ). In all vitiliginous lesions examined with FAV, the erythrocytes within the capillaries of the papillary dermis were the only visible structures (Figure a).…”
supporting
confidence: 81%
“…Regulatory T cells (Treg cells) appear to play a role in preventing and controlling disease. Patients with immune polyendocrinopathy and X‐linked syndrome, who lack Treg cells, are at increased risk for vitiligo . Further research into the mechanism underlying the tolerance breakdown in vitiligo will help provide insight into disease targets and how to best approach treatment.…”
Section: Programmed Cell Death Protein 1 and Vitiligomentioning
confidence: 99%
“…Ob es sich hier um eine Koinzidenz oder eine echte Assoziation handelt, ist nicht abschließend geklärt. Die Inzidenz der Vitiligo in der Normalbevölkerung entspricht mit 0,5–2 % der Häufigkeit, die wir in unserer Zusammenfassung für die FFA‐Patienten ermittelt haben .…”
Section: Diskussionunclassified