Infectious Disease Clinics of North America volume 23, issue 3, P665-681 2009 DOI: 10.1016/j.idc.2009.04.010 View full text
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David J. Ritchie, Bryan T. Alexander, Patrick M. Finnegan

Abstract: Timely provision of adequate antimicrobial coverage in an initial anti-infective treatment regimen results in optimal outcomes for bacterial and fungal infections. However, selection of appropriate antimicrobial regimens for treatment of infections in the intensive care unit (ICU) can be challenging due to expansion of resistance, which typically requires use of multidrug anti-infective regimens to provide adequate coverage of important pathogens commonly seen in the ICU setting. Indeed, a recent additional ca…

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