Neutrophilic eccrine hidradenitis associated with Hodgkin's disease and chemotherapy. A case report

Beutner, K. R.

doi:10.1001/archderm.122.7.809

Cited by 19 publications

(8 citation statements)

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“…However, NEH also develop in patients with other underlying malignancies, such as Hodgkin’s disease, non-Hodgkin’s lymphoma, chronic lymphocytic leukemia, acute lymphoblastic leukemia and cancers [3, 4, 7, 8, 9, 10, 11, 13, 28, 31]. These patients received various chemotherapeutic drugs, such as bleomycin, cisplatin, cyclophosphamide, etoposide, thioguanine, dactinomycin and methotrexate.…”

Section: Discussionmentioning

confidence: 99%

“…Fifty-three cases have been reported until now in the literature and this condition is mainly found in patients receiving chemotherapy regimens with anthracyclins or cytarabine for acute myelogenous leukemia [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38]. This finding has led some authors to hypothesize that NEH could represent a peculiar reaction to cytotoxic drugs excreted in sweat.…”

Section: Introductionmentioning

confidence: 99%

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Recurrent Neutrophilic Eccrine Hidradenitis in an HIV-1-Infected Patient

2000

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Most cases of neutrophilic eccrine hidradenitis (NEH) have been reported in patients receiving chemotherapy for acute myelogenous leukemia or other malignant diseases. We report the case of an HIV-1-infected patient who presented several and strikingly similar episodes of NEH without any medication as well as another one after the first course of chemotherapy for a B-cell non-Hodgkin’s lymphoma. This case strengthens the hypothesis that NEH may occur in different situations, as reported for other neutrophilic dermatoses.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Recurrent Neutrophilic Eccrine Hidradenitis in an HIV-1-Infected Patient

2000

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“…This condition is frequently associated with the combination of certain chemotherapeutic agents including bleomycin, cytarabine, doxorubicin, vincristine, cisplatin and dacarbazine. 84,85 There are various possible mechanisms: for example, NEH may result from the effects of drug toxicity on sweat glands, or may be part of the neutrophilic dermatitis spectrum, or may represent a paraneoplastic condition. Histology of bleomycin-injected human skin also showed necrosis of the eccrine epithelium associated prominently with neutrophilic infiltrates, in a condition resembling NEH.…”

Section: Neutrophilic Eccrine Hidradenitismentioning

confidence: 99%

Bleomycin and the skin

Yamamoto

2006

British Journal of Dermatology

121

111

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Bleomycin is frequently used as a chemotherapeutic agent to treat various kinds of malignancy. However, the cytotoxic effects of bleomycin cause a number of adverse responses, in particular in the lung and the skin. Bleomycin is used by dermatologists as a treatment for various skin cancers, recalcitrant warts, keloid and hypertrophic scars. This article discusses the use of bleomycin for various skin disorders, as well as the risk factors and cutaneous side-effects resulting from its use.

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“…The most commonly implicated drug is cytarabine followed by bleomycin, mitoxantrone, chlorambucil, zidovudine and acetaminophen. [4]…”

Section: Introductionmentioning

confidence: 99%

Neutrophilic eccrine hidradenitis: A new culprit-carbamazepine

et al. 2013

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Neutrophilic eccrine hidradenitis (NEH) is a distinctive dermatosis occurring in patients with malignancy or undergoing chemotherapy. This disorder is characterized by a neutrophilic infiltrate around the eccrine glands and secretory coils, and is associated with necrosis. It must be distinguished from infections, drug eruptions, malignancies or other forms of skin diseases. As it is a self-limiting condition, establishing the diagnosis will avoid unnecessary investigations and treatment. Here we report a case of NEH in a 40-year-old woman suspected to be due to carbamazepine.

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Neutrophilic eccrine hidradenitis associated with Hodgkin's disease and chemotherapy. A case report

Cited by 19 publications

References 0 publications

Recurrent Neutrophilic Eccrine Hidradenitis in an HIV-1-Infected Patient

Recurrent Neutrophilic Eccrine Hidradenitis in an HIV-1-Infected Patient

Bleomycin and the skin

Neutrophilic eccrine hidradenitis: A new culprit-carbamazepine

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