Neutropenic enterocolitis as a presenting complication of acute lymphoblastic leukemia: an unusual case marked by delayed perforation of the descending colon

Wilson, David B.; Rao, Aarati; Hulbert, Monica L.; Mychaliska, Kerry P.; Luchtman‐Jones, Lori; Hill, D. Ashley; Foglia, Robert P.

doi:10.1016/j.jpedsurg.2004.03.083

Cited by 7 publications

(2 citation statements)

References 15 publications

(11 reference statements)

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“…Progression of bowel ischaemia after exploratory laparotomy requiring ‘second-look’ surgery has been described [ 33 ] as well as recurrence of NC after conservatively treated episodes that required surgical treatment [ 36 , 39 ].…”

Section: Neutropenic Colitis (Typhlitis)mentioning

confidence: 99%

International Society of Paediatric Surgical Oncology (IPSO) Surgical Practice Guidelines

Abib¹,

Chui²,

Cox³

et al. 2022

ecancer

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Most children with tumors will require one or more surgical interventions as part of the care and treatment, including making a diagnosis, obtaining adequate venous access, performing a surgical resection for solid tumors (with staging and reconstruction), performing procedures for cancer prevention and its late effects, and managing complications of treatment; all with the goal of improving survival and quality of life. It is important for surgeons to adhere to sound pediatric surgical oncology principles, as they are closely associated with improved local control and survival. Unfortunately, there is a significant disparity in survival rates in low and middle income countries, when compared to those from high income countries.The International Society of Paediatric Surgical Oncology (IPSO) is the leading organization that deals with pediatric surgical oncology worldwide. This organization allows experts in the field from around the globe to gather and address the surgical needs of children with cancer. IPSO has been invited to contribute surgical guidance as part of the World Health Organization Initiative for Childhood Cancer. One of our goals is to provide surgical guidance for different scenarios, including those experienced in High-(HICs) and Low-and Middle-Income Countries (LMICs). With this in mind, the following guidelines have been developed by authors from both HICs and LMICs. These have been further validated by experts with the aim of providing evidence-based information for surgeons who care for children with cancer.We hope that this initiative will benefit children worldwide in the best way possible.

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Section: Neutropenic Colitis (Typhlitis)mentioning

confidence: 99%

International Society of Paediatric Surgical Oncology (IPSO) Surgical Practice Guidelines

Abib¹,

Chui²,

Cox³

et al. 2022

ecancer

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“…In patients who developed, PCI after transplantation, high dose chemotherapy used in the conditioning regimen, steroids, GVHD, neutropenic enterocolitis, and septic shock are accused of being the factors that may play a role in the development of PCI. 3,5,[12][13][14][15][16] . The…”

Section: Discussionmentioning

confidence: 99%

Pneumatosis cystoides intestinalis: A rare complication after hematopoietic stem cell transplantation

Bilir

Demir

Akcabelen

et al. 2021

Pediatric Transplantation

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Background Pneumatosis cystoides intestinalis (PCI) is a disorder in which widespread air sacs are present in mucosa, submucosa, subserosa, and intraabdominal area of the intestinal wall. It has a heterogeneous clinical presentation as a rare complication of intestinal graft‐versus‐host disease (GVHD). Computed tomography is the preferred imaging method for the diagnosis. Since the air sacs could be ruptured spontaneously, the presence of free air in the peritoneal cavity does not confirm intestinal perforation. The conservative treatment approach is sufficient in cases that do not require urgent surgical intervention, such as perforation or obstruction. Case Here, we present a 2.5‐year‐old patient diagnosed with primary hemophagocytic lymphohistiocytosis (pHLH), who underwent allogeneic hematopoietic stem cell transplantation from a matched unrelated donor (MUD) and developed PCI secondary to intestinal GVHD 14th months after HSCT. Conclusions Pneumatosis cystoides intestinalis, which is a rare complication, should be kept in mind, especially in patients with intestinal GVHD and receiving intensive immunosuppressive, octreotide, and steroid treatment after HSCT.

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Recent advances in neutropenic enterocolitis: Insights into the role of gut microbiota

2022

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Neutropenic enterocolitis as a presenting complication of acute lymphoblastic leukemia: an unusual case marked by delayed perforation of the descending colon

Cited by 7 publications

References 15 publications

International Society of Paediatric Surgical Oncology (IPSO) Surgical Practice Guidelines

International Society of Paediatric Surgical Oncology (IPSO) Surgical Practice Guidelines

Pneumatosis cystoides intestinalis: A rare complication after hematopoietic stem cell transplantation

Recent advances in neutropenic enterocolitis: Insights into the role of gut microbiota

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