Neurophysiological Patterns of Search and Creative Behavior in Patients with Psychoactive Substance-Induced Disorders

Abstract

The correlation between search and creative behavior with parameters of bioelectric brain activity was observed in patients with addictive disorders. The prevalence of α- and θ-activities in the parietal-temporal-occipital areas of the cortex and increased θ-activity in the right hemisphere in addiction patients with high search and creative activities were associated with enhanced high-frequency activity in these brain areas. These changes can reflect the formation of a focus of pathologically increased excitation related to the pathogenic mechanisms of addictive disorders.

Role of olfactory reactions, nociception, and immunoendocrine shifts in addictive disorders

“…At onset of dependence EEG alterations of frequency ranges of bioelectrical activity of the brain occur . In animal studies and clinical studies, it was shown that changes of the level of dopamine involved in pathogenesis of addictive disorders are accompanied by shifts of EEG parameters .…”