Neuromusculoskeletal modeling-based evaluation of physical treatment outcomes: Assessing how an exoskeleton rehabilitation treatment affects people with PD

Romanato, M.; Fichera, Fulvia; Pegolo, E.; Spolaor, Fabiola; Volpe, Daniele; Sawacha, Z.

doi:10.1016/j.gaitpost.2022.07.132

Cited by 1 publication

(6 citation statements)

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“…A total of 22.2% of the included studies had a poor quality [32][33][34][35][36][37][38][39], 55.5% had a fair quality [24,[40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58] and 22.2% had a good quality [59][60][61][62][63][64][65][66] [Appendix B].…”

Section: Studies' Methodological Qualitymentioning

confidence: 99%

“…The included studies consisted of retrospective, prospective interventional, or observational research conducted in single or multi-center settings [Supplementary Materials (Tables S1-S3)]. A total of 17 studies investigated functional abilities [33,34,36,42,46,47,49,51,53,54,56,57,[59][60][61]63,65] [Table S1 in Supplementary Material], 23 investigated IC [32][33][34][35][36][37]42,45,47,49,50,52,53,[55][56][57][58][59][60][61][62][63]65] [Table S2 in Supplementary Material], and 26 investigated performance indicators [24,33,[35][36][37][38]…”

Section: Demographic and Study Characteristicsmentioning

confidence: 99%

“…These studies covered a range of conditions, with ten investigating LLE use in patients with stroke [24,45,46,51,54,56,59,[63][64][65], four focusing on patients with Parkinson's Disease (PD) [38,58,60,61], two examining patient cohorts with various other neurological conditions [50,52], three centered on patients with osteoarthritis [42,53,57], and one each for hip fracture [34], sarcopenia [49], and depression [55]. Additionally, there were 14 studies involving healthy older adults [32,33,[35][36][37][39][40][41]43,44,47,48,62,66] [Supplementary Materials (Tables S1-S3)].…”

Section: Demographic and Study Characteristicsmentioning

confidence: 99%

“…The impact of lower limb exoskeletons (LLEs) on various performance indicators has been the subject of extensive research, with multiple studies shedding light on their effects in different populations [24,38,42,46,51,53,54,[56][57][58][59]61,[63][64][65] [Table S3 in Supplementary Materials].…”

Section: Lles To Improve Performance Indicatorsmentioning

confidence: 99%

“…Fifteen studies investigated locomotor performance indicators [24,38,42,46,51,53,54,[56][57][58][59]61,[63][64][65] [Table S3 in Supplementary Material].…”

Section: Lles To Improve Locomotor Performance Indicatorsmentioning

confidence: 99%

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A State-of-the-Art of Exoskeletons in Line with the WHO’s Vision on Healthy Aging: From Rehabilitation of Intrinsic Capacities to Augmentation of Functional Abilities

Gavrila Laic,

Firouzi,

Claeys

et al. 2024

Sensors

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The global aging population faces significant health challenges, including an increasing vulnerability to disability due to natural aging processes. Wearable lower limb exoskeletons (LLEs) have emerged as a promising solution to enhance physical function in older individuals. This systematic review synthesizes the use of LLEs in alignment with the WHO’s healthy aging vision, examining their impact on intrinsic capacities and functional abilities. We conducted a comprehensive literature search in six databases, yielding 36 relevant articles covering older adults (65+) with various health conditions, including sarcopenia, stroke, Parkinson’s Disease, osteoarthritis, and more. The interventions, spanning one to forty sessions, utilized a range of LLE technologies such as Ekso®, HAL®, Stride Management Assist®, Honda Walking Assist®, Lokomat®, Walkbot®, Healbot®, Keeogo Rehab®, EX1®, overground wearable exoskeletons, Eksoband®, powered ankle–foot orthoses, HAL® lumbar type, Human Body Posturizer®, Gait Enhancing and Motivation System®, soft robotic suits, and active pelvis orthoses. The findings revealed substantial positive outcomes across diverse health conditions. LLE training led to improvements in key performance indicators, such as the 10 Meter Walk Test, Five Times Sit-to-Stand test, Timed Up and Go test, and more. Additionally, enhancements were observed in gait quality, joint mobility, muscle strength, and balance. These improvements were accompanied by reductions in sedentary behavior, pain perception, muscle exertion, and metabolic cost while walking. While longer intervention durations can aid in the rehabilitation of intrinsic capacities, even the instantaneous augmentation of functional abilities can be observed in a single session. In summary, this review demonstrates consistent and significant enhancements in critical parameters across a broad spectrum of health conditions following LLE interventions in older adults. These findings underscore the potential of LLE in promoting healthy aging and enhancing the well-being of older adults.

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Section: Studies' Methodological Qualitymentioning

confidence: 99%

Section: Demographic and Study Characteristicsmentioning

confidence: 99%

Section: Demographic and Study Characteristicsmentioning

confidence: 99%

Section: Lles To Improve Performance Indicatorsmentioning

confidence: 99%

“…Fifteen studies investigated locomotor performance indicators [24,38,42,46,51,53,54,[56][57][58][59]61,[63][64][65] [Table S3 in Supplementary Material].…”

Section: Lles To Improve Locomotor Performance Indicatorsmentioning

confidence: 99%

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