Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients

Taquet, Maxime; Sillett, Rebecca; Zhu, Lena; Mendel, Jacob; Camplisson, Isabella; Dercon, Quentin; Harrison, Paul J.

doi:10.1016/s2215-0366(22)00260-7

Cited by 442 publications

(471 citation statements)

References 28 publications

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“…54 Neurocognitive and Mental Health Disease An analysis of retrospective cohort studies examined neurological and psychiatric sequelae of COVID-19 occurring primarily in outpatients up to two years after COVID-19 diagnosis 57. People with a confirmed diagnosis of COVID-19 were propensity-score matched with a 9.64-12.53) cases per 1,000 people at 12 months; a 39% increased risk of depressive disorders beyond 30 days of infection (HR 1.39, 95% CI 1.34-1.43), translating to a reported excess burden of 15.12 (95% CI 13.38-16.91) cases per 1,000 people at 12 months; and a 20% increased risk of substance use disorders (HR 1.20, 95% CI 1.15-1.26), translating to a reported excess burden of 4.34 (95% CI 3.22-5.51) cases per 1,000 people at 12 months, compared to more than 10 million contemporary and historical controls, and 72,207 people with seasonal influenza 56.…”

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confidence: 99%

Understanding the Post COVID-19 Condition (Long COVID) in Adults and the Expected Burden for Ontario

Quinn¹,

Katz²,

Bobos³

et al. 2022

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About Us: The Ontario COVID-19 Science Advisory Table is a group of scientific experts and health system leaders who evaluate and report on emerging evidence relevant to the COVID-19 pandemic, to inform Ontario's response. Our mandate is to provide weekly summaries of relevant scientific evidence for the COVID-19 Health Coordination Table of the Province of Ontario, integrating information from existing scientific tables, Ontario's universities and agencies, and the best global evidence. The Science Table summarizes its findings for the Health Coordination Table and the public in Science Briefs.

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mentioning

confidence: 99%

Understanding the Post COVID-19 Condition (Long COVID) in Adults and the Expected Burden for Ontario

Quinn¹,

Katz²,

Bobos³

et al. 2022

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“…Depression, anxiety, and fatigue, symptoms very often associated with long-COVID-19, were not found connected to MCD (Andriuta et al 2022 ; Alonso-Lana et al 2020 ; Almeria et al 2020 ). A very comprehensive research has been recently published by Taquet and Coworkers (Taquet et al 2022 ). They performed a 2-year study on about 1.3 million patients.…”

Section: Neurological Consequences Of Long-covid-19mentioning

confidence: 99%

“…The scenario changed with the delta and omicron variant infections; in these cases, cognitive problems, insomnia, and intracranial hemorrhage were prevalent in children. The result of the study is very useful to predict sequelae problems correlated to SARS-CoV-2 infection (Taquet et al 2022 ). Furlan Damiano and Collaborators found a positive correlation between chemosensory problems (hypogeusia and parosmia) and cognitive dysfunction performing a neurobiological study on a statistical sample composed by 700 hospitalized mild-to-severe COVID-19 patients.…”

Section: Neurological Consequences Of Long-covid-19mentioning

confidence: 99%

Neurological Consequences, Mental Health, Physical Care, and Appropriate Nutrition in Long-COVID-19

et al. 2022

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SARS-CoV-2 pandemic has caused a collapse of the world health systems. Now, vaccines and more effective therapies have reversed this crisis but the scenario is further aggravated by the appearance of a new pathology, occurring as SARS-CoV-2 infection consequence: the long-COVID-19. This term is commonly used to describe signs and symptoms that continue or develop after acute infection of COVID-19 up to several months. In this review, the consequences of the disease on mental health and the neurological implications due to the long-COVID are described. Furthermore, the appropriate nutritional approach and some recommendations to relieve the symptoms of the pathology are presented. Data collected indicated that in the next future the disease will affect an increasing number of individuals and that interdisciplinary action is needed to counteract it.

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“…COVID-19 can cause serious long-term sequelae, even among vaccinated individuals, 1 and cumulative reinfections increase the risk of hospitalization, mortality, and post-acute sequelae. 2 Moreover, the burdens of COVID-19 have disproportionately harmed lower-income and racially and ethnically diverse people.…”

Section: Masks and Other Non-pharmaceutical Interventions Can Complem...mentioning

confidence: 99%

Community-based N95 Distribution During the COVID-19 Omicron BA.1 Surge: 1-month Utilization and Price Implications

Moran¹,

Dun²,

Kim³

et al. 2022

Preprint

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Masks and other non-pharmaceutical interventions can complement vaccines and treatments as a part of multilayered mitigation to reduce the burden of COVID-19 surges. Accordingly, the investigators distributed 2,500 N95s in 5-packs with informational handouts during the BA.1 surge in New Orleans, Louisiana, USA (12/13/21-1/17/22). Recipients completed a voluntary 1- month follow-up utilization survey (N=153). At 1-month follow-up, participants had used an average of 3.42 (68.4%) of the five N95s, felt safer wearing N95s (Ps<.0001), and discussed N95s with others (80.4%). A cumulative 87.9% would wear N95s again if free. Purchase intentions were price sensitive. After our distribution program, the U.S. federal government distributed free N95s, but stockpiles are depleting, and N95s are not included in ongoing policy plans. Federal governments can prepare for winter surges and new variants by developing policy plans for the ongoing distribution of free N95s.

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Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients

Cited by 442 publications

References 28 publications

Understanding the Post COVID-19 Condition (Long COVID) in Adults and the Expected Burden for Ontario

Understanding the Post COVID-19 Condition (Long COVID) in Adults and the Expected Burden for Ontario

Neurological Consequences, Mental Health, Physical Care, and Appropriate Nutrition in Long-COVID-19

Community-based N95 Distribution During the COVID-19 Omicron BA.1 Surge: 1-month Utilization and Price Implications

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