Neurologic Manifestations of Cat-Scratch Disease

Abstract

Encephalitis is the most frequent neurologic manifestation of cat-scratch disease although myelitis and radiculitis may occur. Recovery is usually if not always complete. The causative agent of cat-scratch disease remains unknown although viruses of the psittacosis-ornithosis-lymphogranuloma venereum-trachoma group and herpes simplex are implicated. The pathogenesis of the neurologic manifestations is obscure. (25:23-27, 1971)

Human bartonellosis: seroepidemiological and clinical features with an emphasis on data from Brazil - A review

“…Neurological complications -Several neurological manifestations of Bartonella infections have been described (Lyon 1971, Carithers & Margileth 1991. They are, in order of frequency: seizures with encephalopathy, status epilepticus and coma, neuroretinitis, aseptic meningitis, transverse myelitis, radiculitis, cerebral arteritis, acute hemiplegia, and dementia (Stevens 1952, Selby & Walker 1979, Miller & Bell 1980, Carithers 1985, Lewis & Tucker 1986, Baker et al 1995, Hadley et al 1995, Hamilton et al 1995, Noah et al 1995, Schwartzman et al 1995, Riviello & Ruoff 1998, Walter & Eppes 1998, Hmaimess et al 2004, Rocha et al 2004, Stockmeyer et al 2007, Baylor et al 2007).…”

Abcès du coude révélant la maladie des griffes du chat: à propos d’un cas

“…Les formes atypiques de la maladie des griffes du chat surviennent chez l'enfant immunodéprimé mais aussi immunocompétent. La maladie peut alors revêtir différents aspects : atteinte ophtalmologique (syndrome oculoganglionnaire de Parinaud) [ 7 ], systémique (Dans ce contexte, une atteinte neurologique, hépatosplénique ou osseuse peut exister) [ 8 ], ou parfois une forme pseudotumorale [ 3 ] ou abcédée comme celle rapportée dans notre observation. Il s'agit le plus souvent d'une masse localisée au niveau des parties molles épargnant généralement l'os.…”

The Clinical Profile of Cat-Scratch Disease’s Neuro-Ophthalmological Effects

“…The majority of individuals with CSD who have central nervous system damage are children under the age of 18. One of the most common symptoms is encephalitis, although radiculitis, polyneuritis, myelitis, and cranial nerve involvement have all been described [90,91]. Neurologic alterations often occur about two weeks after the start of fever and significant lymphadenopathy, which are frequent in these patients.…”