Neurointensive care biophysiological monitoring: Table 1

Dhawan, Vikram; DeGeorgia, Michael

doi:10.1136/neurintsurg-2011-010158

Cited by 18 publications

(13 citation statements)

References 123 publications

(91 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…is extraordinarily metabolically active,s uch that its oxygen consumption rates are high;o xygen tensions in the frontal white matter typically average 40 mmHg,b ut values ranging from 33 to 48 mmHg and beyond have been reported. [2,3] Likewise,m uscle tissues exhibit pO 2 values of 25-32 mmHg, depending on the depth, muscle type,a nd muscle location. [2] Reported pO 2 values of the liver also exhibit awide range and dependence on the physiological state.W hereas transplant recipients exhibit elevated liver pO 2 values of 60 mmHg 48 hours after the transplant, intraoperative pO 2 values recorded using ad ifferent method showed am edian pO 2 value of 31 mmHg.…”

Section: Overview: Mechanisms Of Oxygen Consumption Utilization Andmentioning

confidence: 99%

Oxygen‐Sensing Methods in Biomedicine from the Macroscale to the Microscale

et al. 2015

View full text Add to dashboard Cite

Oxygen monitoring has been a topic of exhaustive study given its central role in the biochemistry of life. The ability to quantify the physiological distribution and real-time dynamics of oxygen from sub-cellular to macroscopic levels is required to fully understand the mechanisms associated with both normal physiology and disease states. This Review will present the most significant recent advances in the development of oxygen-sensing materials and techniques, including polarographic, nuclear medicine, magnetic resonance, and optical approaches, that can be applied specifically for the real-time monitoring of oxygen dynamics in cellular and tissue environments. As some of the most exciting recent advances in synthetic methods and biomedical applications have been in the field of optical oxygen sensors, a major focus will be on the development of these toolkits.

show abstract

Section: Overview: Mechanisms Of Oxygen Consumption Utilization Andmentioning

confidence: 99%

Oxygen‐Sensing Methods in Biomedicine from the Macroscale to the Microscale

et al. 2015

View full text Add to dashboard Cite

show abstract

“…The cellular, molecular and structural changes associated with the primary (physical) and secondary (biological) responses to the injury manifest in functional changes observed clinically. These changes include a whole array of altered physiological responses, for example, decreased cerebral perfusion, depressed glucose metabolism, altered water balance, edema, among others, and neurobehavioral changes ranging from dizziness, confusion and memory impairment to loss of consciousness [32]. These clinically observed signs and symptoms change over time post TBI leading to the ever-increasing amounts of clinical data.…”

Section: Traumatic Brain Injurymentioning

confidence: 99%

“…Neurointensive care units (NICU) generate very large volumes of data collected during continuous monitoring of vitals, physiological and biochemical parameters such as cerebral perfusion pressure, cerebral blood flow, brain tissue oxygenation, intracranial pressure, changes in intracranial glucose metabolism, among others[32,39]. Combined with the outputs of various imaging modalities, EEGs and other diagnostic monitoring, each patient generates staggering amounts of data during the NICU stay.…”

Section: Current Use Of Bd In Tbimentioning

confidence: 99%

Big Data in traumatic brain injury; promise and challenges

Agoston

Langford

2017

Concussion

View full text Add to dashboard Cite

Traumatic brain injury (TBI) is a spectrum disease of overwhelming complexity, the research of which generates enormous amounts of structured, semi-structured and unstructured data. This resulting big data has tremendous potential to be mined for valuable information regarding the “most complex disease of the most complex organ”. Big data analyses require specialized big data analytics applications, machine learning and artificial intelligence platforms to reveal associations, trends, correlations and patterns not otherwise realized by current analytical approaches. The intersection of potential data sources between experimental TBI and clinical TBI research presents inherent challenges for setting parameters for the generation of common data elements and to mine existing legacy data that would allow highly translatable big data analyses. In order to successfully utilize big data analyses in TBI, we must be willing to accept the messiness of data, collect and store all data and give up causation for correlation. In this context, coupling the big data approach to established clinical and pre-clinical data sources will transform current practices for triage, diagnosis, treatment and prognosis into highly integrated evidence-based patient care.

show abstract

“…Unlike cerebral angiography and TCD, these techniques measure regional perfusion, not merely diameter of blood vessels or flow velocities. [24] Hence, these techniques predict clinical outcome better, but the drawback is that at present, these are not routinely available.…”

Section: Vasospasmmentioning

confidence: 99%

Principles of neuroanesthesia in aneurysmal subarachnoid hemorrhage

Kundra

Mahendru

Gupta

et al. 2014

J Anaesthesiol Clin Pharmacol

View full text Add to dashboard Cite

Aneurysmal subarachnoid hemorrhage is associated with high mortality. Understanding of the underlying pathophysiology is important as early intervention can improve outcome. Increasing age, altered sensorium and poor Hunt and Hess grade are independent predictors of adverse outcome. Early operative interventions imposes an onus on anesthesiologists to provide brain relaxation. Coiling and clipping are the two treatment options with increasing trends toward coiling. Intraoperatively, tight control of blood pressure and adequate brain relaxation is desirable, so that accidental aneurysm rupture can be averted. Patients with poor grades tolerate higher blood pressures, but are prone to ischemia whereas patients with lower grades tolerate lower blood pressure, but are prone to aneurysm rupture if blood pressure increases. Patients with Hunt and Hess Grade I or II with uneventful intraoperative course are extubated in operation theater, whereas, higher grades are kept electively ventilated. Postoperative management includes attention toward fluid status and early management of vasospasm.

show abstract

Neurointensive care biophysiological monitoring: Table 1

Cited by 18 publications

References 123 publications

Oxygen‐Sensing Methods in Biomedicine from the Macroscale to the Microscale

Oxygen‐Sensing Methods in Biomedicine from the Macroscale to the Microscale

Big Data in traumatic brain injury; promise and challenges

Principles of neuroanesthesia in aneurysmal subarachnoid hemorrhage

Contact Info

Product

Resources

About