Neurocognitive function in borderline personality disorder

Dinn, Wayne M.

doi:10.1016/j.pnpbp.2003.10.012

Cited by 78 publications

(63 citation statements)

References 69 publications

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“…Prefrontal disruption is consistent with evidence of the heightened vulnerability of the left neocortex to early life stressors [55][56][57] , that have been implicated in BPD pathogenesis 4 . Similarly, cognitive deficits implicating the lateral prefrontal cortex have also been shown in BPD including deficits in working memory, visuo-constructive abilities and non-verbal executive function 58 .…”

Section: Dorsolateral Prefrontal Cortexmentioning

confidence: 96%

Amygdala and dlPFC abnormalities, with aberrant connectivity and habituation in response to emotional stimuli in females with BPD

Dudás

Mole

Morris

et al. 2017

Journal of Affective Disorders

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dlPFC abnormalities, with aberrant connectivity and habituation in response to emotional stimuli in females with BPD, Journal of Affective Disorders, http://dx.doi.org/10.1016Disorders, http://dx.doi.org/10. /j.jad.2016 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Section: Dorsolateral Prefrontal Cortexmentioning

confidence: 96%

Amygdala and dlPFC abnormalities, with aberrant connectivity and habituation in response to emotional stimuli in females with BPD

Dudás

Mole

Morris

et al. 2017

Journal of Affective Disorders

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“…BPD patients have shown deficits in verbal and nonverbal (visual) memory, visual perception, visuomotor speed, rhythm reproduction, complex cognitive tasks involving multistep, multielement, associative operations (e.g. delayed memory, similarity comparisons, and proverb interpretations) [40][41][42][43][44][45][46][47][48][49][50][51][52][53][54] , visuospatial function, attention [51,[55][56][57][58] , emotion recognition [59] , and executive dysfunctions like planning, cognitive flexibility and decision making under uncertainty [60] . BPD patients' attentional deficits appear to primarily affect conflict resolution, indicating impaired frontal functioning, rather than other attentional functions like alertness [57] .…”

Section: Neuropsychological Findings In Bpdmentioning

confidence: 99%

“…For example, several authors found that compared to healthy controls, BPD patients had deficits in visual/nonverbal memory [55,79] , executive functions (planning, flexibility, fluency), especially on nonverbal tasks [55,60,79] , and visuospatial functions [53,58,79,80] . Monarch et al [49] found that relative to healthy controls, BPD inpatients were impaired in attention/vigilance and verbal learning and memory domains which implicate the frontosubcortical and temporolimbic brain regions.…”

Section: Prefrontal Dysfunctionmentioning

confidence: 99%

Neuropsychobiological Aspects, Comorbidity Patterns and Dimensional Models in Borderline Personality Disorder

et al. 2010

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Borderline personality disorder (BPD) is a comorbid and disabling condition with high prevalence in psychiatric settings. The pathogenesis of BPD involves complex interactions among genetic, neurobiological and environmental factors, resulting in multiple core symptom domains such as emotional dysregulation, impulse dyscontrol, aggression, cognitive dysfunctions and dissociative states. Neurobiological studies show that symptoms and behaviors of BPD are partly associated with alterations in glutamatergic, dopaminergic and serotonergic systems. In addition, neuroimaging studies in BPD patients indicate differences in the volume and activity of specific brain regions related to emotion and impulse control, such as the prefrontal and cingulate cortex, amygdala and hippocampus. Neurobiological alterations are related to cognitive disturbances in patients with BPD and neuropsychological tests have shown abnormalities of memory, attention, language, and executive functions. The aim of the present review is to provide an updated overview of the main neuropsychobiological aspects of BPD and their relation to clinical symptoms, comorbidity patterns and dimensional models.

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“…-Déficits no controle inibitório (Lieb et al, 2004). -Déficits na flexibilidade cognitiva, planejamento, inibição de respostas e tomada de decisão (Dinn et al, 2004;Ruocco, 2005).…”

Section: T De Personalidade Tipo Borderlineunclassified

O desempenho executivo em pacientes que apresentam automutilação

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AGRADECIMENTOSÀ Deus em profunda gratidão.À minha orientadora, Sandra Scivoletto, pelo apoio, incentivo e por não desistir deste projeto, mesmo diante de tantas dificuldades minhas.Aos colegas do AMITI, em especial ao Dr Hermano Tavares, pelo apoio, incentivo e confiança para a realização deste trabalho; e à equipe da triagem pelo carinho e ajuda na apliacação e mensuração dos testes neuropsicológicos.À amiga Jackeline Giusti, pelo apoio, incentivo, ajuda na aplicação dos questionários e atendimentos destes pacientes. Além das preciosas contribuições para a construção deste trabalho, do artigo e da minha vida.Aos colegas do PROTOC que ajudaram no treino dos questionários.À estatística Melina Oliveira pela paciência e indispensável ajuda dos cálculos estatísticos.Ao instituto de psiquiatria da FMUSP por oferecer toda estrutura para a realização desta pesquisa.À Eliza e Isabel, da Pós-graduação do Instituto de Psiquitria, pelo apoio, orientação e paciência com as obrigações burocráticas.À Maria Umbelina, da Biblioteca do Instituto de Psiquiatria, por todo cuidado, atenção e prontidão com os artigos solicitados.A todas as pessoas que aceitaram participar da pesquisa, pacientes e controles, pela confiança e apoio.Aos meus pais, Ana Clara e Onézimo, pelo amor, suporte, incentivo e por acreditarem em mim.Ao meu irmão Annderson e sua família (Caroline, Pedro, Sofia e Lucas), pelo amor, apoio e incentivo incondicional.Ao Eduardo, por todo carinho, paciência e suporte em todas as etapas.Aos meus familiares, por todo apoio, apesar da distância.Aos meus amigos que sempre estiveram ao meu lado, mesmo quando estavam distantes. Em especial a Raissa

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Neurocognitive function in borderline personality disorder

Cited by 78 publications

References 69 publications

Amygdala and dlPFC abnormalities, with aberrant connectivity and habituation in response to emotional stimuli in females with BPD

Amygdala and dlPFC abnormalities, with aberrant connectivity and habituation in response to emotional stimuli in females with BPD

Neuropsychobiological Aspects, Comorbidity Patterns and Dimensional Models in Borderline Personality Disorder

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