Neuro-ophthalmic Features of Cerebral Venous Obstruction

Abstract

The clinical manifestation of impaired cerebral venous outflow vary depending on the underlying mechanism. Although most patients maintain good vision, more aggressive treatment is sometimes indicated in patients with thrombosis or compression. The abrupt onset and marked severity of symptoms in patients with thrombosis should help to differentiate these patients from those with idiopathic intracranial hypertension.

Long-Term Prognosis of Cerebral Vein and Dural Sinus Thrombosis

“…However, the total number of surveyed pregnancies remains small. Contrary to some retrospective studies [14], but in accordance with the results of Preter et al [1], Purvin et al [15] and Biousse et al [16], the risk of visual loss was very low, although constriction of visual fields was not evaluated.…”

Long-Term Prognosis of Cerebral Vein and Dural Sinus Thrombosis

“…However, the total number of surveyed pregnancies remains small. Contrary to some retrospective studies [14], but in accordance with the results of Preter et al [1], Purvin et al [15] and Biousse et al [16], the risk of visual loss was very low, although constriction of visual fields was not evaluated.…”

Cerebral venous thrombosis presenting as acute visual loss

“…The sluggish light reflex with normal disc appearance for this patient may indicate optic nerve dysfunction secondary to acute IICP. Although acute IICP itself may result in transient visual obscuration, severe visual loss only complicates end stage IICP with optic atrophy 2. On the other hand, CVT associated venous infarction involving the bilateral primary visual cortex may lead to cortical blindness; however, for the present case, the rapid recovery of vision and the absence of any low density regions representing cerebral infarction over the left P-O region on the follow up brain CT excluded such a possibility.…”

Patterns and Outcomes of Acute Central Nervous System Complications During Treatment of Childhood Acute Lymphoblastic Leukemia: A Single-center Experience

“…As for predictors of outcome in the current study, patients who developed visual disturbances were associated with unfavorable outcomes. Ophthalmological manifestations such as diplopia, affected visual acuity, or defective visual field are caused mainly due to increased intracranial pressure, and may be complicated by optic nerve atrophy 16 . Visual disorientation, psychic gaze paralysis, and inferior altitudinal hemianopsia may develop if cerebral infarction is complicated in the parieto-occipital region 17 .…”

“…Ophthalmological manifestations such as diplopia, affected visual acuity, or defective visual field are caused mainly due to increased intracranial pressure, and may be complicated by optic nerve atrophy. 16 Visual disorientation, psychic gaze paralysis, and inferior altitudinal hemianopsia may develop if cerebral infarction is complicated in the parietooccipital region. 17 Eclampsia may cause transient blindness due to occipital edema, which can be resolved within 24 hours after giving medication to reduce cerebral edema and does not affect the outcome of the affected patient.…”

Long-Term Prognosis of Cerebral Vein and Dural Sinus Thrombosis

“…However, the total number of surveyed pregnancies remains small. Contrary to some retrospective studies [14], but in accordance with the results of Preter et al [1], Purvin et al [15] and Biousse et al [16], the risk of visual loss was very low, although constriction of visual fields was not evaluated.…”

Cerebral venous thrombosis presenting as acute visual loss

“…The sluggish light reflex with normal disc appearance for this patient may indicate optic nerve dysfunction secondary to acute IICP. Although acute IICP itself may result in transient visual obscuration, severe visual loss only complicates end stage IICP with optic atrophy 2. On the other hand, CVT associated venous infarction involving the bilateral primary visual cortex may lead to cortical blindness; however, for the present case, the rapid recovery of vision and the absence of any low density regions representing cerebral infarction over the left P-O region on the follow up brain CT excluded such a possibility.…”

Patterns and Outcomes of Acute Central Nervous System Complications During Treatment of Childhood Acute Lymphoblastic Leukemia: A Single-center Experience

“…As for predictors of outcome in the current study, patients who developed visual disturbances were associated with unfavorable outcomes. Ophthalmological manifestations such as diplopia, affected visual acuity, or defective visual field are caused mainly due to increased intracranial pressure, and may be complicated by optic nerve atrophy 16 . Visual disorientation, psychic gaze paralysis, and inferior altitudinal hemianopsia may develop if cerebral infarction is complicated in the parieto-occipital region 17 .…”

“…Ophthalmological manifestations such as diplopia, affected visual acuity, or defective visual field are caused mainly due to increased intracranial pressure, and may be complicated by optic nerve atrophy. 16 Visual disorientation, psychic gaze paralysis, and inferior altitudinal hemianopsia may develop if cerebral infarction is complicated in the parietooccipital region. 17 Eclampsia may cause transient blindness due to occipital edema, which can be resolved within 24 hours after giving medication to reduce cerebral edema and does not affect the outcome of the affected patient.…”

Long-Term Prognosis of Cerebral Vein and Dural Sinus Thrombosis

“…However, the total number of surveyed pregnancies remains small. Contrary to some retrospective studies [14], but in accordance with the results of Preter et al [1], Purvin et al [15] and Biousse et al [16], the risk of visual loss was very low, although constriction of visual fields was not evaluated.…”

Cerebral venous thrombosis presenting as acute visual loss

“…The sluggish light reflex with normal disc appearance for this patient may indicate optic nerve dysfunction secondary to acute IICP. Although acute IICP itself may result in transient visual obscuration, severe visual loss only complicates end stage IICP with optic atrophy 2. On the other hand, CVT associated venous infarction involving the bilateral primary visual cortex may lead to cortical blindness; however, for the present case, the rapid recovery of vision and the absence of any low density regions representing cerebral infarction over the left P-O region on the follow up brain CT excluded such a possibility.…”

Patterns and Outcomes of Acute Central Nervous System Complications During Treatment of Childhood Acute Lymphoblastic Leukemia: A Single-center Experience

“…As for predictors of outcome in the current study, patients who developed visual disturbances were associated with unfavorable outcomes. Ophthalmological manifestations such as diplopia, affected visual acuity, or defective visual field are caused mainly due to increased intracranial pressure, and may be complicated by optic nerve atrophy 16 . Visual disorientation, psychic gaze paralysis, and inferior altitudinal hemianopsia may develop if cerebral infarction is complicated in the parieto-occipital region 17 .…”

“…Ophthalmological manifestations such as diplopia, affected visual acuity, or defective visual field are caused mainly due to increased intracranial pressure, and may be complicated by optic nerve atrophy. 16 Visual disorientation, psychic gaze paralysis, and inferior altitudinal hemianopsia may develop if cerebral infarction is complicated in the parietooccipital region. 17 Eclampsia may cause transient blindness due to occipital edema, which can be resolved within 24 hours after giving medication to reduce cerebral edema and does not affect the outcome of the affected patient.…”