Neue Untersuchungen zur Konstitution von Isatin‐Thiophen‐Indophenin und Isatin‐Pyrrol‐Indophenin

Pindur, U.

doi:10.1002/ardp.19813140409

Cited by 2 publications

(3 citation statements)

References 13 publications

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“…These compounds are formed as a mixture of geometric isomers 448 , and may possess one or two thiophene units; the latter being the major product 449 (Scheme 111).…”

Section: Scheme 110mentioning

confidence: 99%

The chemistry of isatins: a review from 1975 to 1999

Silva¹,

Garden²,

Pinto³

2001

J. Braz. Chem. Soc.

828

434

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Isatinas (1H-indol-2,3-diona) são compostos de grande versatilidade sintética, podendo ser utilizados na obtenção de diversos sistemas heterociclos, como derivados indólicos e quinolínicos, o que as tornam importantes matérias-primas na síntese de fármacos. Isatinas também têm sido detectadas em tecidos de mamíferos, o que tem despertado o interesse em seu estudo como moduladores em diversos processos bioquímicos. Os avanços na aplicação de isatinas em síntese orgânica, bem como na compreensão de seus efeitos biológicos e farmacológicos nos últimos vinte e cinco anos encontram-se relatados nesta revisão e seus respectivos materiais suplementares.Isatins (1H-indole-2,3-dione) are synthetically versatile substrates, where they can be used for the synthesis of a large variety of heterocyclic compounds, such as indoles and quinolines, and as raw material for drug synthesis. Isatins have also been found in mammalian tissue and their function as a modulator of biochemical processes has been the subject of several discussions. The advances in the use of isatins for organic synthesis during the last twenty-five years, as well as a survey of its biological and pharmacological properties are reported in this review and in the accompanying supplementary information.

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“…These compounds are formed as a mixture of geometric isomers 448 , and may possess one or two thiophene units; the latter being the major product 449 (Scheme 111).…”

Section: Scheme 110mentioning

confidence: 99%

The chemistry of isatins: a review from 1975 to 1999

Silva¹,

Garden²,

Pinto³

2001

J. Braz. Chem. Soc.

828

434

View full text Add to dashboard Cite

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“…C23H16N204 requires M , 384.1 110); h,,,, 262 and 565 nm (log E 4.25 and 4.50); vmax. 1 775, 1 705, 1625, and 1 593 cm '; m/z 384 ( M + , 40%), 342 (59,325 (5), 314 (7), 313 (lo), 286 (8), 285 (8), 158 (loo), 130 (20), and 103 (15). 8.44/8.49 (1 H, d, J 3 Hz, 2-H), 8.1 1 (1 H, d, J 8 Hz, 7-H), 7.6-…”

Section: (D) a Solution Of 4-( 1 -Acetylindol-3-yl)-4-hydroxybut-3-enoicmentioning

confidence: 99%

“…> 290 "C (Found: C, 70.6; H, 4.4; N, 11.4. C2,H1,N30, requires C, 70.6; H, 4.2; N, 11.75%); m/z 357 ( M ' , loo%), 329 (3), 314 (12), 286 (lo), 212 (12), 179 (lo), 157 (7), 143 (12), 117 (lo), and 44 (47).…”

Section: (D) a Solution Of 4-( 1 -Acetylindol-3-yl)-4-hydroxybut-3-enoicmentioning

confidence: 99%

Spectroscopic properties of violacein and related compounds: crystal structure of tetramethylviolacein

Laatsch¹,

Thomson²,

Cox³

1984

J. Chem. Soc., Perkin Trans. 2

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Violacein and deoxyviolacein have been isolated from cultures of Alteromonas luteoviolacea. The violacein-type lactams (1) and lactones (3) have a merocyanine chromophore w h i c h was confirmed b y the effects of substituents on the visible spectra and b y HMO calculations. Using parameters derived from an X-ray crystal structure analysis of tetramethylviolacein, PPP calculations of the electronic spectra of violacein and isoviolacein derivatives showed good agreement with observed values.

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Neue Untersuchungen zur Konstitution von Isatin‐Thiophen‐Indophenin und Isatin‐Pyrrol‐Indophenin

Cited by 2 publications

References 13 publications

The chemistry of isatins: a review from 1975 to 1999

The chemistry of isatins: a review from 1975 to 1999

Spectroscopic properties of violacein and related compounds: crystal structure of tetramethylviolacein

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