DOI: 10.1001/archinte.1972.03650030119027 View full text |Buy / Rent full text

Abstract: Heimbach and Crout in the Archives (129:430, 1972) found that the atropine-induced increase of heart rate was diminished in hyperthyroid subjects as compared to normals. They then approached the conclusion that tonic vagal inhibition is reduced in hyperthyroidism.This conclusion would be more nearly valid if they had ruled out, through appropriate controls, the initial value effect described by Wilder1: when an initial value is high (pulse for example), a drug or other influence which raises the value has a s… Show more

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