Nephroprotective effects of ferulic acid, Z-ligustilide and E-ligustilide isolated from Angelica sinensis against cisplatin toxicity in vitro

Bunel, Valérian; Antoine, Marie-Hélène; Nortier, Joëlle; Duez, Pierre; Stévigny, Caroline

doi:10.1016/j.tiv.2014.12.017

Cited by 59 publications

(32 citation statements)

References 47 publications

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“…4). The ferulic acid is a powerful antioxidant with neuroprotective properties in several models of studies [12], but its anticonvulsant effect has not been reported in previous studies. But analyzing the studies of Zhang et al [16], it was demonstrated that the ferulic acid ( Additionally, this ester derivative of ferulic acid did not cause deficits of the motor coordination and muscle relaxation activities in mice by rod route test when treated in doses that produced an anticonvulsant effect, unlike observed for DZP.…”

Section: A N U S C R I P Tmentioning

confidence: 87%

“…Among these compounds, stands out the ferulic acid that presents several pharmacological activities such as neuroprotective [12], antidiabetic [13], anticancer [14] anti-inflammatory [15], antidepressant [16,17] and mainly antioxidant [18]. In addition, the development of their derivatives that comprise similar chemical structure are promising in relation to a range of new pharmacological properties on the central M A N U S C R I P T A C C E P T E D ACCEPTED MANUSCRIPT 4 nervous system, which may be related to neuroprotective action [19,20,21].…”

Section: Introductionmentioning

confidence: 99%

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Anticonvulsant and behavioral effects observed in mice following treatment with an ester derivative of ferulic acid: Isopentyl ferulate

Machado

Oliveira

Machado

et al. 2015

Chemico-Biological Interactions

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Section: A N U S C R I P Tmentioning

confidence: 87%

Section: Introductionmentioning

confidence: 99%

Anticonvulsant and behavioral effects observed in mice following treatment with an ester derivative of ferulic acid: Isopentyl ferulate

Machado

Oliveira

Machado

et al. 2015

Chemico-Biological Interactions

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“…(E/Z)-3pentenal and 4-pentenal [44][45][46][47][48][49][50] are attractive intermediates for the production of valuable C6 compounds such as adipic acid, hexamethylenediamine and 1,6-hexanediol via the selective conversion of 1,6-hexanedial (adipaldehyde) as a central intermediate ( Figure 19). [51][52][53] Many research groups investigated hydroformylation of butadiene experimentally. In recent decades, however, the selectivity for adipic aldehyde has been low, which has led to further research.…”

Section: 2 Carbonylationmentioning

confidence: 99%

“…In recent decades, however, the selectivity for adipic aldehyde has been low, which has led to further research. [45][46][47][48][49][50][51][52][53][54][55] The highest reported selectivities to adipaldehyde in butadiene hydroformylation so far is 50 %. [56] The use of chelating bisphosphite ligands, as congeners of the bisphosphine triptyphos (TTP), and rhodium-based catalysts shows high n-selectivity in reactions of 1-alkenes.…”

Section: 2 Carbonylationmentioning

confidence: 99%

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Homogeneously Catalyzed 1,3‐Diene Functionalization – A Success Story from Laboratory to Miniplant Scale

et al. 2018

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For many years, the efficient use of resources has been a major and permanent challenge for the chemical industry. The implementation of alternative resources such as renewables and carbon dioxide has been a subject of considerable discussion, but also the more efficient use of long known bulk chemicals is of great interest. Among them, 1,3‐dienes such as 1,3‐butadiene from the C4 cut of the naphtha cracker as well as isoprene, piperylene and cyclopentadiene from the corresponding C5 section are important substrates. These dienes are presently employed in various markets, with the greatest importance being in the production of polymers and copolymers. However, homogeneous transition metal catalysis has proven to be a versatile tool to functionalize these important 1,3‐dienes to low molecular weight fine chemicals by introducing, for example, nitrogen, oxygen or silicon. Hence, an upgraded use of the corresponding products as agrochemicals, pharmaceuticals, fragrances or special detergents is close at hand. The main approaches in the topic of homogeneous functionalization reactions of the industrially relevant 1,3‐dienes will be summarized and discussed within the present article. Besides that, novel applications including renewable 1,3‐dienes, for example β‐myrcene and β‐farnesene, as well as the application of CO2 in telomerization, will be critically discussed.

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et al. 2019

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Neuroblastoma (NB) is a serious disease with high-risk and poor prognosis in children. Survivors often have serious side effects. Angelica polysaccharide (AP) has been proved to exert antitumor function. Therefore, we explored the mechanism of this function in NB to accelerate the clinical application of AP in NB therapy. SH-SY5Y cells were transfected with miR-205 inhibitor and pretreated by AP. Cell activity, colonies number, and apoptosis were detected via Cell Counting Kit-8 assay, colony formation experiment, and flow cytometry, respectively. Targeting link between miR-205 and zinc finger E-box binding homeobox 1 (ZEB1) was measured via luciferase activity assay. Quantitative reverse transcription polymerase chain reaction and western blot was to examine levels of miR-205 and related factors. We found that AP suppressed cell activity and colony formation, whereas induced apoptosis in SH-SY5Y cells. Besides, AP also suppressed Epithelialmesenchymal transition process and phosphatidylinositol 3 kinase (PI3K)/protein kinase B (AKT) and extracellular signal-regulated kinase (ERK1/2) signal passageways. Additionally, miR-205 was positively regulated by AP. AP played its antitumor functions through up-regulating miR-205. Target of miR-205 was ZEB1. Our study demonstrated that AP played its antitumor role in NB through positively regulation of miR-205, whose target gene was ZEB1.

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Nephroprotective effects of ferulic acid, Z-ligustilide and E-ligustilide isolated from Angelica sinensis against cisplatin toxicity in vitro

Cited by 59 publications

References 47 publications

Anticonvulsant and behavioral effects observed in mice following treatment with an ester derivative of ferulic acid: Isopentyl ferulate

Anticonvulsant and behavioral effects observed in mice following treatment with an ester derivative of ferulic acid: Isopentyl ferulate

Homogeneously Catalyzed 1,3‐Diene Functionalization – A Success Story from Laboratory to Miniplant Scale

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