Neoplastic skin lesions of the scalp in children: A retrospective study of 265 cases in Taiwan

Yang, Chao‐Chun; Chen, Yi‐An; Tsai, Yi‐Lin; Shih, I‐Hsin; Chen, WenChieh

doi:10.1684/ejd.2013.2216

Cited by 10 publications

(6 citation statements)

References 32 publications

(33 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The comparison among similar series is summarized in Table III. A few reports consisted only of malignant tumors of the scalp (6-10) and one was performed on a pediatric population (11). In our study, we found that the majority of malignant scalp tumors occurred in middle-aged and elderly individuals, which is consistent with the previous reports (6-10).…”

Section: Discussionsupporting

confidence: 92%

Scalp Lesions Referred For Surgical Procedures: Single-Center 5-year Experience in Southwestern Poland

Chlebicka

Stefaniak

Gawdzik

et al. 2020

In Vivo

View full text Add to dashboard Cite

Background/Aim: The head is a body site with a particular predisposition to skin malignancies due to exposure to UV radiation. The aim of the study was to better elucidate the characteristics of skin lesions that develop on the scalp. Patients and Methods: A retrospective review of all excised and histologically assessed lesions of the scalp at a single dermatosurgery unit throughout a fiveyear period was performed. Demographic features and lesion characteristics were compiled and analyzed. Results: Among 5,601 procedures during the analyzed period, 293 were performed on lesions on the scalp area (5.2%) with a mean patient age of 66±19.7 years. The defects were closed, mainly using primary closure, followed by skin grafts, and, least often, flaps (65.1%, 28.5%, 4.9%, respectively). Two thirds of the excised scalp lesions were histologically confirmed as malignant scalp tumors (mostly basal cell carcinomas followed by squamous cell carcinomas). Conclusion: The vast majority of scalp lesions referred for surgical procedures appeared to be malignant. Therefore, dermatologists should pay special attention to the scalp by examining it thoroughly, as the lesions may be hidden by hair. The head is a body site with a particular predisposition to skin malignancies (1-3). This is due to its frequent exposure to ultraviolet radiation (UV). Tumors in the area of the scalp may be overlooked due to long hair or their occipital or postauricular location. Additionally, UV exposure of the frontal area as well as other scalp areas in patients with androgenetic alopecia is very high (1, 3). This study aimed to provide the characteristics of a group of subjects treated at the Dermatosurgery Unit of the Department of Dermatology, Venereology and Allegrology of Wroclaw Medical University in Poland for scalp lesions with particular reference to age, sex, amount, location and surgical methods of treatment.

show abstract

Section: Discussionsupporting

confidence: 92%

Scalp Lesions Referred For Surgical Procedures: Single-Center 5-year Experience in Southwestern Poland

Chlebicka

Stefaniak

Gawdzik

et al. 2020

In Vivo

View full text Add to dashboard Cite

show abstract

“…265,271 There is a diffuse and dense dermal infiltrate with extension into the subcutaneous tissue ( Figure 14). 4,234,263,264,[268][269][270]272 A Grenz zone is typically present with epidermal sparing. Cytologically, the infiltrate consists of small lymphoblasts with scant cytoplasm, fine nuclear chromatin, irregular nuclei, and inconspicuous nucleoli.…”

Section: Precursor T/b-cell Lymphoblastic Leukemias/ Lymphomasmentioning

confidence: 99%

“…Some cases of JXG follow the diagnosis of LCH. 272,[396][397][398][399][400][401][402] More recently, systemic presentations of JXG with CNS involvement have shown BRAF V600E mutations. 386,387 The question that arises from these is: Should those cases be qualified as ECD/L group lesions that have not presented themselves with systemic findings (ie, brain only), or is there a truly separate group of JXG/BRAF V600E positive tumors?…”

Section: Langerhans Cell Histiocytosismentioning

confidence: 99%

See 1 more Smart Citation

Cutaneous Hematolymphoid and Histiocytic Proliferations in Children

Gru

Dehner

2018

Pediatr Dev Pathol

View full text Add to dashboard Cite

This article focuses on cutaneous hematopoietic neoplasms that are more likely to be encountered in the pediatric age-group and includes both lymphoproliferative and histiocytic disorders. The cutaneous hematologic disorders in children have a different epidemiologic profile to what is seen during adulthood. Although mycosis fungoides is the most frequent form of cutaneous lymphoma in adults, it is very rare in children. Because lymphoblastic leukemias and lymphomas are more frequent in the pediatric setting, cutaneous leukemic infiltrates are relatively common in this age-group. Similarly, histiocytic disorders are more common in children, particularly Langerhans cell histiocytosis and juvenile xanthogranuloma. Notably, the histiocytic disorders have undergone significant modifications on their nomenclature in the basis of the molecular characteristics that are present in them. A summary of the most frequent cutaneous hematopoietic disorders in children will be discussed further in this review.

show abstract

“…This meta-analysis produced an incidence of secondary malignancy lower than studies published before 2000 (with reported rates of development of BCC up to 14% 25,27 ), being more consistent with recent publications. 4,11,38,42,44 Several reasons for this discrepancy exist. First, earlier studies may have misdiagnosed basaloid proliferations as BCC.…”

Section: Malignant Lesionsmentioning

confidence: 99%

Rate of Benign and Malignant Secondary Tumors Associated With Nevus Sebaceous

Pang,

Cevik,

Sreedharan

et al. 2024

Ann Plast Surg

View full text Add to dashboard Cite

Background Nevus sebaceous (NS) is a rare congenital skin lesion affecting approximately 0.3% of all newborns. Although benign, NS lesions can harbor malignant secondary tumors. The published rate of development of these malignant tumors varies. This meta-analysis aimed to identify the rate of malignant and benign secondary neoplasms occurring in NS. Methods A literature search was conducted using PubMed, Embase, and Web of Science from inception to April 2023. Eligible studies reported incidence or risk of secondary neoplasms in patients with NS. Two independent reviewers screened studies, extracted data, and assessed the quality of included studies. The primary outcome was the pooled incidence of secondary neoplasms. Studies with sample sizes greater than 50 patients were eligible for meta-analysis using the random-effects model. Results Twenty-eight studies were identified, 22 of which were eligible for meta-analysis. The overall rate of secondary neoplasms was 12.8% (95% confidence interval [Cl], 9.2%–17.6%). The rates of development of malignant and benign tumors were 2.4% (95% CI, 1.4%–4.1%) and 10.3% (95% CI, 7.5%–13.9%), respectively. The rate of development of basal cell carcinoma was 1.7% (95% CI, 0.9%–3.2%), whereas the rate of the development of syringocystadenoma papilliferum was 3.6% (95% CI, 2.5%–5.3%) and that if trichoblastoma was 2.6% (95% CI, 1.7%–3.8%). Conclusions Although the rate of development of malignant tumors within a primary NS lesion is low, it is not negligible. Prophylactic early excision remains a viable approach to prevent secondary malignant neoplasms, address cosmetic and functional complications, and preempt the need for complex reconstruction in the future. We propose that resection of NS lesions in childhood remains a reasonable first-line option in the appropriate patient keeping in mind that it may leave an undesirable scar.

show abstract

Neoplastic skin lesions of the scalp in children: A retrospective study of 265 cases in Taiwan

Cited by 10 publications

References 32 publications

Scalp Lesions Referred For Surgical Procedures: Single-Center 5-year Experience in Southwestern Poland

Scalp Lesions Referred For Surgical Procedures: Single-Center 5-year Experience in Southwestern Poland

Cutaneous Hematolymphoid and Histiocytic Proliferations in Children

Rate of Benign and Malignant Secondary Tumors Associated With Nevus Sebaceous

Contact Info

Product

Resources

About