Neonatal short bowel syndrome

Current Status of Intestinal Failure and Intestinal Transplantation

“…The loss of colonic length has a relatively modest effect on the necessity for long-term parenteral nutrition. In general, the primary function of the colon is fluid and electrolyte absorption [10]. The search for a biomarker to predict the adaptive ability of the intestine is critical with regard to prognosis and the decision to transplant or continue rehabilitative efforts.…”

Recent Advances in Neonatal Gastroenterology and Neonatal Nutrition

“…The primary aetiologies of SBS in neonatal population are: Necrotizing enterocolitis, intestinal atresias, gastroschisis, malrotation with volvulus, and Hirschprung's disease that extends into the small bowel (Gutierrez et al 2011). …”

“…The treatment for suspected bacterial overgrowth is the administration of enteral antibiotics in a cyclical fashion. Antibiotics that are commonly used include those effective against anaerobes or Gram-negative organisms (Gutierrez et al 2011). Systemically non absorbable antibiotics are preferred.…”

Nutritional management in a neonate with Short Bowel Syndrome: a case report from NICU, Tata Main Hospital, Jamshedpur

“…As per available epidemiological data, the prevalence of surgical SBS was 0.7% in very low birth weight (VLBW) infants born during the period 2002-2005 at the National Institute of Child Health and Development (NICHD) neonatal research network centres [2]. Similarly data from a Canadian tertiary NICU shows an overall occurrence of SBS as 22.1 per 1000 admissions, and 24.5 per 100,000 live births, incidence being higher in infants born at less than 37 weeks gestation (353.7 per 100,000 live births) than in full-term infants (3.5/100,000 live births) [3].Necrotizing enterocolitis (NEC) is the most common cause of SBS (35%) in neonates, followed by intestinal atresia (25%), gastroschisis (18%), malrotation with volvulus (14%), followed by less common conditions such as Hirschsprung's disease with proximal extension of aganglionosis into the small bowel (2%) [4]. Studies show that in the absence of surgical bowel lengthening procedures, an infant with about 35 cm of residual small bowel has a 50% probability of being weaned from parenteral nutrition [5].…”