2008
DOI: 10.1016/s1875-9572(08)60015-7
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Abstract: Neonatal gastric perforation is associated with high mortality, particularly in premature infants. There is also a trend towards higher mortality in lower-birth-weight infants.

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Cited by 57 publications
(90 citation statements)
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“…Also, a number of other theories have been proposed to explain these events, including hypoxic stress leading to gastric ischemia by selective shunting of blood away from the splanchnic vascular bed, sepsis, and mechanical rupture of the stomach secondary to increased gastric pressure due to lack of coordination or immaturity of the vomiting mechanism in infants. The use of positive pressure ventilation or nasal continuous positive airway pressure without decompression of the stomach and treatment with steroid therapy for bronchopulmonary dysplasia are other possible causes [1,5,7]. Because of known gastric hyperacidity in the first few days of life and gastric stress ulcers that have been reported in a variety of critically ill infants, it has been proposed that perforation can result from the transmural necrosis of such lesions [8].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Also, a number of other theories have been proposed to explain these events, including hypoxic stress leading to gastric ischemia by selective shunting of blood away from the splanchnic vascular bed, sepsis, and mechanical rupture of the stomach secondary to increased gastric pressure due to lack of coordination or immaturity of the vomiting mechanism in infants. The use of positive pressure ventilation or nasal continuous positive airway pressure without decompression of the stomach and treatment with steroid therapy for bronchopulmonary dysplasia are other possible causes [1,5,7]. Because of known gastric hyperacidity in the first few days of life and gastric stress ulcers that have been reported in a variety of critically ill infants, it has been proposed that perforation can result from the transmural necrosis of such lesions [8].…”
Section: Discussionmentioning
confidence: 99%
“…Legar et al reported the first successful repair of gastric perforation in a newborn in 1950 [1,2]. The etiology and pathogenesis of gastric perforation in the neonatal period are still unknown, although premature birth and low birth weight are known risk factors.…”
Section: Introductionmentioning
confidence: 99%
“…Neonatal gastric perforation is extremely rare and associated with poor prognosis [1,2,4]. Various theories have been proposed describing the etiology and prognosis but it still remains obscure [1][2][3]5].…”
Section: Discussionmentioning
confidence: 99%
“…Various factors and theories have been proposed as a possible cause [1][2][3][4][5][6][7] but the etiology still remains obscure. Gastric perforations are often large and associated with necrosis of a significant portion of the stomach wall.…”
Section: Introductionmentioning
confidence: 99%
“…Перфорации в результате про-бодения желудочных язв желудка крайне редки у маленьких детей. Стандартный подход к лечению этого состояния предполагает использование лапа-ротомии [25].…”
Section: дискуссияunclassified